Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

Messenger roles of extracellular vesicles during fertilization of gametes, development and implantation: Recent advances

W Fan, Y Qi, Y Wang, H Yan, X Li… - Frontiers in Cell and …, 2023 - frontiersin.org
Extracellular vesicles (EVs) have become a research hotspot in recent years because they
act as messengers between cells in the physiological and pathological processes of the …

Isolation, characterization, proteome, miRNAome, and the embryotrophic effects of chicken egg yolk nanovesicles (vitellovesicles)

IM Saadeldin, BM Tanga, S Bang, C Seo… - Scientific Reports, 2023 - nature.com
Egg yolk constitutes about a third of the structure of the chicken egg however, the molecular
structure and physiological effects of egg yolk-derived lipid membranous vesicles are not …

Follicular fluid-derived extracellular vesicles influence on in vitro maturation of equine oocyte: impact on cumulus cell viability, expansion and transcriptome

J Gabryś, A Gurgul, T Szmatoła, B Kij-Mitka… - International Journal of …, 2024 - mdpi.com
Cumulus cell (CC) expansion is pivotal for oocyte maturation, during which CCs release
factors that initiate paracrine signaling within the follicular fluid (FF). The FF is abundant in …

Effects of extracellular vesicles derived from steroids-primed oviductal epithelial cells on porcine in vitro embryonic development

S Bang, AY Qamar, X Fang, H Kim, A Han, H Kang… - Theriogenology, 2023 - Elsevier
Extracellular vesicles (EVs) play an active role in regulating different physiological events,
however, endocrine control of EVs cargo contents remain poorly understood. In this study …

Oviductal extracellular vesicles miRNA cargo varies in response to embryos and their quality

M Hamdi, JM Sánchez, B Fernandez-Fuertes… - BMC genomics, 2024 - Springer
Background Increasing evidence points to an active role of oviductal extracellular vesicles
(oEVs) in the early embryo-maternal dialogue. However, it remains unclear whether oEVs …

Extracellular vesicles affecting embryo development in vitro: a potential culture medium supplement

Y Xue, H Zheng, Y Xiong, K Li - Frontiers in Pharmacology, 2024 - frontiersin.org
Extracellular vesicles (EVs) are nanometer-sized lipid bilayer vesicles released by cells,
playing a crucial role in mediating cellular communication. This review evaluates the effect …

Information Flow between Parents and Offspring Is Essential for Successful Development

WV Holt, J Gadea - Biomolecules, 2023 - mdpi.com
Over the last several decades, the sciences of developmental biology and physiology have
expanded and intertwined their scope enormously. Where once it might have been …

The role of reproductive tract extracellular vesicles on boar sperm function

Z Xu, K Zhang, Y Yang, H Chang, F Wen, X Li - Theriogenology, 2024 - Elsevier
Extracellular vesicles (EVs) are abundant in reproductive tract fluids and serve as important
mediators of paracrine communication, influencing the function of gametes. Sperm undergo …

[HTML][HTML] Swine in vitro embryo production: Potential, challenges, and advances

M Garcia-Canovas, I Parrilla, C Cuello, MA Gil… - Animal Reproduction …, 2024 - Elsevier
Pig production, a vital sector of the meat industry, faces demands for improved quality,
efficiency, and sustainability. Advancements in breeding, disease control, and artificial …