Brainstem tumors represent 10–15% of pediatric central nervous system tumors and diffuse
intrinsic pontine glioma (DIPG) is the most common brainstem tumor of childhood. DIPG is …

Glioblastoma multiforme (GBM) or astrocytoma grade Ⅳ on WHO classification is the most
aggressive and the most frequent of all primary brain tumors. Glioblastoma is multiforme …

Conventional, anatomical MRI is an essential tool for diagnosis and evaluation of location,
quality, and extent of posterior fossa tumors, but offers limited information regarding tumor …

Purpose Diffuse intrinsic pontine glioma (DIPG) is the most aggressive primary pediatric
brain tumor, with< 10% of children surviving 2 years. Radiation therapy (RT) remains the …

OBJECTIVE Recent studies have shed light on the molecular makeup of diffuse intrinsic
pontine gliomas and led to the identification of potential treatment targets for these lesions …

Pediatric diffuse intrinsic pontine glioma (DIPG) represents approximately 20% of all
pediatric CNS tumors. However, disease outcomes are dismal with a median survival of less …

Purpose To analyze the pathways to brainstem tumors in childhood, as well as safe entry
zones. Method We conducted a retrospective study of 207 patients less than 18 years old …

BACKGROUND: The feasibility and safety of stereotactic biopsy for brainstem tumors (BSTs)
are controversial. Although magnetic resonance imaging (MRI) has been reported as the …

Diffuse intrinsic pontine glioma (DIPG) is an extensively invasive malignancy with infiltration
into other regions of the brainstem. Although large numbers of specific targeted therapies …

Pediatric brainstem gliomas include low-grade focal brainstem gliomas (FBSG) and high-
grade diffuse intrinsic pontine gliomas (DIPG). These tumors share a crucial and eloquent …