Intra-articular drug delivery: the challenge to extend drug residence time within the joint
SHR Edwards - The Veterinary Journal, 2011 - Elsevier
The rationale behind developing sustained release microsphere formulations of non-
steroidal anti-inflammatory drugs (NSAIDs) administered via the intra-articular (IA) route is to …
steroidal anti-inflammatory drugs (NSAIDs) administered via the intra-articular (IA) route is to …
The use of intra‐articular corticosteroids in the horse: what is known on a scientific basis?
CW McIlwraith - Equine veterinary journal, 2010 - Wiley Online Library
Intra‐articular use of corticosteroids has become a recent focus (or re‐focus) of attention in
the Thoroughbred racing industry. This manuscript reviews the clinical use and scientific …
the Thoroughbred racing industry. This manuscript reviews the clinical use and scientific …
Clinicopathologic findings following intra-articular injection of autologous and allogeneic placentally derived equine mesenchymal stem cells in horses
DD Carrade, SD Owens, LD Galuppo, MA Vidal… - …, 2011 - Taylor & Francis
Background aims. The development of an allogeneic mesenchymal stem cell (MSC) product
to treat equine disorders would be useful; however, there are limited in vivo safety data for …
to treat equine disorders would be useful; however, there are limited in vivo safety data for …
Evaluation of a single intra-articular injection of autologous protein solution for treatment of osteoarthritis in horses
AL Bertone, A Ishihara, LJ Zekas… - American journal of …, 2014 - Am Vet Med Assoc
Objective—To evaluate intra-articular autologous protein solution (APS) for the treatment of
osteoarthritis in horses. Animals—40 client-owned horses with naturally occuring …
osteoarthritis in horses. Animals—40 client-owned horses with naturally occuring …
[HTML][HTML] Inflammatory response to the administration of mesenchymal stem cells in an equine experimental model: effect of autologous, and single and repeat doses of …
N Ardanaz, FJ Vázquez, A Romero, AR Remacha… - BMC veterinary …, 2016 - Springer
Abstract Background Mesenchymal stem cells (MSCs) transplantation has become a
promising therapeutic choice for musculoskeletal injuries. Joint-related disorders are highly …
promising therapeutic choice for musculoskeletal injuries. Joint-related disorders are highly …
Analgesic efficacy of intra-articular morphine in experimentally induced radiocarpal synovitis in horses
C Lindegaard, MH Thomsen, S Larsen… - Veterinary anaesthesia …, 2010 - Elsevier
Objective To compare the analgesic effect of intra-articular (IA) and intravenous (IV)
morphine in horses with experimentally induced synovitis. Animals Eight adult horses. Study …
morphine in horses with experimentally induced synovitis. Animals Eight adult horses. Study …
[HTML][HTML] Saussurea lappa Ethanolic Extract Attenuates Triamcinolone Acetonide-Induced Pulmonary and Splenic Tissue Damage in Rats via Modulation of Oxidative …
GI Abd El-Rahman, A Behairy, NM Elseddawy… - Antioxidants, 2020 - mdpi.com
Background: In this era, worldwide interest has been directed towards using natural
antioxidants to guard against drug side effects. Saussurea lappa is a famous medicinal plant …
antioxidants to guard against drug side effects. Saussurea lappa is a famous medicinal plant …
[HTML][HTML] Evaluation of the inflammatory response in experimentally induced synovitis in the horse: a comparison of recombinant equine interleukin 1 beta and …
OBJECTIVE: To compare two transient models of synovitis-osteoarthritis (OA) in horses by
characterizing biological changes in synovial fluid and joint tissue. METHOD: Twelve …
characterizing biological changes in synovial fluid and joint tissue. METHOD: Twelve …
Pain in osteoarthritis
PR van Weeren, JC de Grauw - … Clinics: Equine Practice, 2010 - vetequine.theclinics.com
Osteoarthritis (OA), also known as osteoarthrosis or degenerative joint disease, is the most
important chronic musculoskeletal disorder in both humans and horses. Although not a life …
important chronic musculoskeletal disorder in both humans and horses. Although not a life …
Inflammatory effects of autologous, genetically modified autologous, allogeneic, and xenogeneic mesenchymal stem cells after intra-articular injection in horses
JH Pig, A Ishihara, ML Wellman… - Veterinary and …, 2013 - thieme-connect.com
Objectives: To compare the clinical and inflammatory joint responses to intra-articular
injection of bone marrow-derived mesenchymal stem cells (MSC) including autologous …
injection of bone marrow-derived mesenchymal stem cells (MSC) including autologous …