Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood
The molecular pathology of stress-related disorders remains elusive. Our brain multiregion,
multiomic study of posttraumatic stress disorder (PTSD) and major depressive disorder …
multiomic study of posttraumatic stress disorder (PTSD) and major depressive disorder …
Single-cell genomics and regulatory networks for 388 human brains
Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the
brain. Yet little is understood about how genetic variants influence cell-level gene …
brain. Yet little is understood about how genetic variants influence cell-level gene …
escheR: unified multi-dimensional visualizations with Gestalt principles
The creation of effective visualizations is a fundamental component of data analysis. In
biomedical research, new challenges are emerging to visualize multi-dimensional data in a …
biomedical research, new challenges are emerging to visualize multi-dimensional data in a …
Organizational principles of the primate cerebral cortex at the single-cell level
R Chen, P Nie, L Ma, GZ Wang - bioRxiv, 2024 - biorxiv.org
The primate cerebral cortex, the major organ for cognition, consists of an immense number
of neurons. However, the organizational principles governing these neurons remain unclear …
of neurons. However, the organizational principles governing these neurons remain unclear …