Comparative genomic analysis of esophageal squamous cell carcinoma among different geographic regions

R Zhang, C Li, Z Wan, J Qin, Y Li, Z Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction Esophageal squamous cell carcinoma (ESCC) shows remarkable variation in
incidence, survival, and risk factors. Although the genomic characteristics of ESCC have …

[HTML][HTML] Pan-cancer mutational signature surveys correlated mutational signature with geospatial environmental exposures and viral infections

J Bai, K Ma, S Xia, R Geng, C Shen, L Jiang… - Computational and …, 2023 - Elsevier
Background Cancer has been disproportionally affecting minorities. Genomic-based cancer
disparity analyses have been less common than conventional epidemiological studies. In …

Potent molecular-targeted therapies for advanced esophageal squamous cell carcinoma

A Ooki, H Osumi, K Chin, M Watanabe… - Therapeutic …, 2023 - journals.sagepub.com
Esophageal cancer (EC) remains a public health concern with a high mortality and disease
burden worldwide. Esophageal squamous cell carcinoma (ESCC) is a predominant …

A new approach to the challenging problem of mutational signature attribution

N Jiang, Y Wu, SG Rozen - bioRxiv, 2024 - biorxiv.org
Mutational signatures are characteristic patterns of mutations caused by endogenous
mutational processes or by exogenous mutational exposures. Much research has focused …

Alcohol consumption as a risk factor for oesophageal squamous cell carcinoma risk in sub-Saharan Africa

V Kayamba - The Lancet Global Health, 2022 - thelancet.com
Epidemiological studies from many parts of the world have reported alcohol consumption as
a risk factor for oesophageal squamous cell carcinoma (ESCC) and that this relationship is …

An overview of multiomics: a powerful tool applied in cancer molecular subtyping for cancer therapy

Y Zou, Z Zhao, Y Song - Malignancy Spectrum, 2024 - Wiley Online Library
During the process of carcinogenesis and tumor progression, various molecular alternations
occur in different omics levels. In recent years, multiomics approaches including genomics …

[PDF][PDF] Cohort size required for prognostic genes analysis of stage II/III esophageal squamous cell carcinoma

L Kong, M Yang, Z Wan, L Wang - Pathology and Oncology …, 2023 - por-journal.com
Background: Few overlaps between prognostic biomarkers are observed among different
independently performed genomic studies of esophageal squamous cell carcinoma (ESCC) …

Implication des infections à papillomavirus humains dans la carcinogenèse œsophagienne et endocervicale

C Reynders - 2023 - orbi.uliege.be
Les papillomavirus humains (HPVs) sont des virus à ADN double brin non enveloppés. Le
groupe d'HPVs le plus largement étudié est le groupe des α-HPVs. Séparés des α-HPVs de …

[PDF][PDF] Repetitive exposure to non-typhoidal Salmonellae is an environmental risk factor for colon cancer

DM Van Elsland, JW Duijster… - DRIVER OR …, 2022 - scholarlypublications …
During its infectious cycle, Salmonella exploits its host by targeting and manipulating
essential signalling pathways. This may disrupt cellular integrity and induce oncogenic …

[PDF][PDF] INVESTIGATING THE ROLE OF DNA DAMAGE TOLERANCE IN MUTAGENESIS USING WHOLE-GENOME SEQUENCING

ZT Gyüre - 2023 - repo.lib.semmelweis.hu
Replication of genome is one of the most fundamental phenomena for every living organism.
It requires accurate copying millions or billions of nucleotides in coordination with the cell …