Expression and role of Fc-and complement-receptors on human dendritic cells

Z Bajtay, E Csomor, N Sándor, A Erdei - Immunology letters, 2006 - Elsevier
Dendritic cells (DCs) are professional antigen presenting cells, which take up
pathogens/foreign structures in peripheral tissues, then migrate to secondary lymphoid …

The versatile functions of complement C3‐derived ligands

A Erdei, N Sándor, B Mácsik‐Valent… - Immunological …, 2016 - Wiley Online Library
The complement system is a major component of immune defense. Activation of the
complement cascade by foreign substances and altered self‐structures may lead to the …

HIV‐1 Trans Infection of CD4+ T Cells by Professional Antigen Presenting Cells

CR Rinaldo - Scientifica, 2013 - Wiley Online Library
Since the 1990s we have known of the fascinating ability of a complex set of professional
antigen presenting cells (APCs; dendritic cells, monocytes/macrophages, and B …

[HTML][HTML] Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3

R Ellegård, E Crisci, A Burgener, C Sjöwall… - The Journal of …, 2014 - journals.aai.org
Immature dendritic cells (iDCs) in genital and rectal mucosa may be one of the first cells to
come into contact with HIV-1 during sexual transmission of virus. HIV-1 activates the host …

Utilization of complement receptors in immune cell–microbe interaction

S Lukácsi, B Mácsik‐Valent, Z Nagy‐Baló… - FEBS …, 2020 - Wiley Online Library
The complement system is a major humoral component of immunity and is essential for the
fast elimination of pathogens invading the body. In addition to its indispensable role in …

Complement receptor 3 promotes severe ross river virus-induced disease

TE Morrison, JD Simmons, MT Heise - Journal of virology, 2008 - Am Soc Microbiol
ABSTRACT Alphaviruses such as Ross River virus (RRV) and chikungunya virus are
mosquito-transmitted viruses that cause explosive epidemics of debilitating arthritis and …

Complement-opsonized HIV-1 overcomes restriction in dendritic cells

W Posch, M Steger, U Knackmuss, M Blatzer… - PLoS …, 2015 - journals.plos.org
DCs express intrinsic cellular defense mechanisms to specifically inhibit HIV-1 replication.
Thus, DCs are productively infected only at very low levels with HIV-1, and this non …

HIV‐1 replication in dendritic cells occurs through a tetraspanin‐containing compartment enriched in AP‐3

E Garcia, DS Nikolic, V Piguet - Traffic, 2008 - Wiley Online Library
Dendritic cells (DC) are crucial components of the early events of HIV infection. Dendritic
cells capture and internalize HIV at mucosal surfaces and efficiently transfer the virus to …

Opsonization of HIV with complement enhances infection of dendritic cells and viral transfer to CD4 T cells in a CR3 and DC-SIGN-dependent manner

H Bouhlal, N Chomont, M Réquena… - The Journal of …, 2007 - journals.aai.org
In the present study, we demonstrated that opsonization of primary HIV-1 with human
complement enhances infection of immature monocyte-derived dendritic cells (iDC) and …

Complement and its role in protection and pathogenesis of flavivirus infections

P Avirutnan, E Mehlhop, MS Diamond - Vaccine, 2008 - Elsevier
The complement system is a family of serum and cell surface proteins that recognize
pathogen-associated molecular patterns, altered-self ligands, and immune complexes …