Induction of optimal HIV‐1‐specific T‐cell responses, which can contribute to controlling
viral infection in vivo, depends on antigen processing and presentation processes occurring …

Complement is activated during the early phase of viral infection and promotes destruction
of virus particles as well as the initiation of inflammatory responses. Recently, complement …

Our study demonstrates that binding of complement-opsonized HIV to complement receptor
type 1 on human erythrocytes (E) via C3b fragments is followed by a rapid normal human …

Dendritic cells (DCs) possess intrinsic cellular defense mechanisms to specifically inhibit
HIV-1 replication. In turn, HIV-1 has evolved strategies to evade innate immune sensing by …

Dendritic cells (DCs), natural killer (NK) cells, and T cells play critical roles during primary
HIV-1 exposure at the mucosa, where the viral particles become coated with complement …

Mucosa resident dendritic cells (DCs) may represent one of the first immune cells that HIV-1
encounters during sexual transmission. The virions in body fluids can be opsonized with …

The complement system is an ancient pattern recognition system that becomes activated
during all stages of HIV infection. Previous studies have shown that C5a can enhance the …

[Frontiers in Bioscience 12, 2124-2135, January 1, 2007] 2124 Float on: lipid rafts in the
lifecycle of HIV Doris Wilflingseder Page 1 [Frontiers in Bioscience 12, 2124-2135, January 1 …

Both, HIV envelope proteins gp120 and gp41 can directly activate complement system, even
in the absence of HIV-specific antibodies. During the budding process HIV acquires host …

HIV transmission via genital and colorectal mucosa are the most common routes of
dissemination. Here, we explored the effects of free and complement-opsonized HIV on …