The role of influenza-A virus and coronavirus viral glycoprotein cleavage in host adaptation

MR Heindl, E Böttcher-Friebertshäuser - Current Opinion in Virology, 2023 - Elsevier
While receptor binding is well recognized as a factor in influenza-A virus (IAV) and
coronavirus (CoV) host adaptation, the role of viral glycoprotein cleavage has not been …

Comprehensive analysis and immunohistochemistry localization of NRP1 expression in pancancer and normal individual tissues in relation to SARS‑CoV‑2 …

J Fu, J He, L Zhang, J Cheng… - Experimental and …, 2023 - spandidos-publications.com
Neuropilin 1 (NRP1/CD304) is a typical membrane-bound co-receptor for vascular
endothelial growth factor, semaphorin family members and viral severe acute respiratory …

Prospects of animal models and their application in studies on adaptive immunity to SARS-CoV-2

X Wei, N Rong, J Liu - Frontiers in Immunology, 2022 - frontiersin.org
The adaptive immune response induced by SARS-CoV-2 plays a key role in the antiviral
process and can protect the body from the threat of infection for a certain period of time …

Influence of shear stress, inflammation and BRD4 inhibition on human endothelial cells: A holistic proteomic approach

J Jarausch, L Neuenroth, R Andag, A Leha, A Fischer… - Cells, 2022 - mdpi.com
Atherosclerosis is an important risk factor in the development of cardiovascular diseases. In
addition to increased plasma lipid concentrations, irregular/oscillatory shear stress and …

Correlations between cytokine levels, liver function markers, and neuropilin-1 expression in patients with COVID-19

SA El Kazafy, YM Fouad, AF Said, HH Assal, TM Ali… - Vaccines, 2022 - mdpi.com
Aim: The study evaluated the correlations between cytokine levels, liver function markers,
and neuropilin-1 (NRP-1) expression in patients with COVID-19 in Egypt. The study also …

An update on the interaction between COVID-19, vaccines, and diabetic kidney disease

Y Yang, S Zou, G Xu - Frontiers in Immunology, 2022 - frontiersin.org
Up to now, coronavirus disease 2019 (COVID-19) is still affecting worldwide due to its highly
infectious nature anrapid spread. Diabetic kidney disease (DKD) is an independent risk …

Natural variants in SARS-CoV-2 Spike protein pinpoint structural and functional hotspots with implications for prophylaxis and therapeutic strategies

S Pokhrel, BR Kraemer, S Burkholz… - Scientific reports, 2021 - nature.com
In December 2019, a novel coronavirus, termed severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), was identified as the cause of pneumonia with severe …

COVID-19: a systematic review of the transmissibility, pathogenesis, entry factors, and signature immune response

D Fayyad, JL Kelts, TH Nielson, IL Epelle, NC Monear… - BioChem, 2022 - mdpi.com
Objectives: The emergence of coronavirus disease 2019 (COVID-19), caused by the novel
coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a …

The Effect of Select SARS-CoV-2 N-Linked Glycan and Variant of Concern Spike Protein Mutations on C-Type Lectin-Receptor-Mediated Infection

A Bains, W Guan, PJ LiWang - Viruses, 2023 - mdpi.com
The SARS-CoV-2 virion has shown remarkable resilience, capable of mutating to escape
immune detection and re-establishing infectious capabilities despite new vaccine rollouts …

Impact of SARS-CoV-2 on host factors involved in mental disorders

R Rhoades, S Solomon, C Johnson… - Frontiers in Microbiology, 2022 - frontiersin.org
COVID-19, caused by SARS-CoV-2, is a systemic illness due to its multiorgan effects in
patients. The disease has a detrimental impact on respiratory and cardiovascular systems …