Traditional electron-transfer dissociation (ETD) experiments operate through a complex
combination of hydrogen abundant and hydrogen deficient fragmentation pathways, yielding …

Time-and collision energy-resolved surface-induced dissociation (SID) of peptide radical
anions was studied using a Fourier transform ion cyclotron resonance mass spectrometer …

The biochemical processes responsible for proper cellular operation are wholly dependent
on interactions between biomolecules constructed with canonical yet alterable structures …

Conventional tandem mass spectrometry relies on even-electron fragmentation that
provides limited structural information for glycerophospholipids (GP), which are key …

Accurate identification of fragments in tandem mass spectrometry experiments is aided by
knowledge of relevant fragmentation mechanisms. Herein, novel radical addition reactions …

The ever-changing landscape of mass spectrometry is driven by gaps in knowledge, and
one of the biggest driving forces is the desire to understand the structure and dynamics of …

Rationale One of the major shortcomings of linear ion trap mass spectrometers is poor
resolution. Failure to resolve isotopic peaks makes charge state determination for large …

Photoinitiated radical chemistry has proven to be useful for breaking covalent bonds within
many biomolecules in the gas phase. Herein, we demonstrate that radical chemistry is …

Radical-directed dissociation of gas phase ions is emerging as a powerful and
complementary alternative to traditional tandem mass spectrometric techniques for …

Glycans are fundamental biological macromolecules, yet despite their prevalence and
recognized importance, a number of unique challenges hinder routine characterization. The …