[HTML][HTML] Histology and sperm retrieval among men with Y chromosome microdeletions

W Yuen, AP Golin, R Flannigan… - … andrology and urology, 2021 - ncbi.nlm.nih.gov
In this review of Y chromosome microdeletions, azoospermia factor (AZF) deletion subtypes,
histological features and microTESE sperm retrieval rates are summarized after a systematic …

A systemic review and meta‐analysis exploring the predictors of sperm retrieval in patients with non‐obstructive azoospermia and chromosomal abnormalities

A Majzoub, M Arafa, H Clemens, J Imperial… - Andrologia, 2022 - Wiley Online Library
To identify the most prevalent chromosomal abnormalities in patients with non‐obstructive
azoospermia (NOA), consolidate their surgical sperm retrieval (SSR) rates and determine …

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors

MM Mikedis, Y Fan, PK Nicholls, T Endo, EK Jackson… - Elife, 2020 - elifesciences.org
Fertility across metazoa requires the germline-specific DAZ family of RNA-binding proteins.
Here we examine whether DAZL directly regulates progenitor spermatogonia using a …

Reproductive success of assisted reproductive technology in couples with chromosomal abnormalities

AR Jesus, S Silva-Soares, J Silva, M Severo… - Journal of assisted …, 2019 - Springer
Purpose Infertility is estimated to affect 15% of couples, having chromosome abnormalities
an important role in its etiology. The main objective of this work was to access the …

RNA-binding protein Maca is crucial for gigantic male fertility factor gene expression, spermatogenesis, and male fertility, in Drosophila

L Zhu, R Fukunaga - PLoS genetics, 2021 - journals.plos.org
During spermatogenesis, the process in which sperm for fertilization are produced from
germline cells, gene expression is spatiotemporally highly regulated. In Drosophila …

Clinical, cytogenomic, and molecular characterization of isodicentric y-chromosome and prediction of testicular sperm retrieval outcomes in azoospermic and severe …

U Abur, S Gunes, N Hekim, OS Akar, E Altundag… - Journal of Assisted …, 2022 - Springer
Purpose Sex chromosome abnormalities are associated with male infertility. The aim of this
study was to characterize the clinical, cytogenetic, and molecular findings of 12 infertile men …

Molecular microdeletion analysis of infertile men with karyotypic Y chromosome abnormalities

Y Pan, H Zhang, QI Xi, H Zhang… - Journal of …, 2018 - journals.sagepub.com
Objectives To investigate azoospermic factor (AZF) microdeletions in infertile men from
northeastern China with karyotypic Y chromosome abnormalities. Methods G-banding of …

Chromosomal abnormalities and Y chromosome microdeletions in infertile men with azoospermia and oligozoospermia in Eastern China

J Sha, G Huang, B Zhang, X Wang… - Journal of …, 2020 - journals.sagepub.com
Objective The objective was to investigate the frequency and type of chromosomal
abnormalities and Y chromosome microdeletions in infertile men with azoospermia and …

Clinical and molecular characterization of Y microdeletions and X‐linked CNV 67 implications in male fertility: a 20‐year experience

A Pinho, A Barros, S Fernandes - Andrology, 2020 - Wiley Online Library
Background Approximately 15% of couples worldwide are affected with infertility, attributed
to a male co‐factor in about half of the cases. Y chromosome microdeletions are the second …

Investigation of genotype–phenotype correlation in patients with AZF microdeletion in a single‐reference centre

E Uzay, F Kızılay, B Altay, H Akın, MB Durmaz - Andrologia, 2021 - Wiley Online Library
In this study, we aimed to elucidate the relationship between AZF deletion type and clinical
information of azoospermic patients with AZF microdeletion in the Turkish population …