Oligo-metastatic cancers: putative biomarkers, emerging Challenges and New Perspectives

A Ottaiano, M Santorsola, L Circelli, AM Trotta, F Izzo… - Cancers, 2023 - mdpi.com
Simple Summary Oligometastatic disease is a condition in oncology where cancer affects
only a few distant sites. It is associated with a low-burden spread and a more favorable …

Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future directions

J Zhong, H Bai, Z Wang, J Duan, W Zhuang… - Frontiers of …, 2023 - Springer
With the improved understanding of driver mutations in non-small cell lung cancer (NSCLC),
expanding the targeted therapeutic options improved the survival and safety. However …

Integrated bioinformatics analysis identifies a new stemness index-related survival model for prognostic prediction in lung adenocarcinoma

S Hou, H Xu, S Liu, B Yang, L Li, H Zhao… - Frontiers in …, 2022 - frontiersin.org
Background: Lung adenocarcinoma (LUAD) is one of the most lethal malignancies and is
currently lacking in effective biomarkers to assist in diagnosis and therapy. The aim of this …

Identification of age‐and immune‐related gene signatures for clinical outcome prediction in lung adenocarcinoma

A Zhou, D Zhang, X Kang, JD Brooks - Cancer Medicine, 2023 - Wiley Online Library
Background The understanding of the factors causing decreased overall survival (OS) in
older patients compared to younger patients in lung adenocarcinoma (LUAD) remains …

Preparation, characterisation, and in vitro cancer‐suppression function of RNA nanoparticles carrying miR‐301b‐3p Inhibitor

J Zhao, N Niu, F Yang, H Liu, W Qi - IET nanobiotechnology, 2023 - Wiley Online Library
Background Multidrug resistance is the biggest barrier on the way to chemotherapy for lung
adenocarcinoma (LUAD). For some LUAD patients with cisplatin (DDP) resistance and poor …

tRNA-derived fragments: mechanism of gene regulation and clinical application in lung cancer

F Wu, Q Yang, W Pan, W Meng, Z Ma, W Wang - Cellular Oncology, 2024 - Springer
Lung cancer, being the most widespread and lethal form of cancer globally, has a high
incidence and mortality rate primarily attributed to challenges associated with early …

[PDF][PDF] Constructing an APOBEC-related gene signature with predictive value in the overall survival and therapeutic sensitivity in lung adenocarcinoma

Y Luo, H Wang, J Zhong, J Shi, X Zhang, Y Yang, R Wu - Heliyon, 2023 - cell.com
Background APOBEC family play an important role in cancer mutagenesis and tumor
development. The role of APOBEC family in lung adenocarcinoma (LUAD) has not been …

ROS1-Rearranged Lung Adenocarcinoma: From Molecular Genetics to Target Therapy

U Testa, G Castelli, E Pelosi - Onco, 2023 - mdpi.com
Simple Summary Receptor tyrosine kinases are present on the cell membrane of some cell
types and are responsible for the regulation of cell growth. These receptors are frequently …

Analysis on methylation and expression of PSMB8 and its correlation with immunity and immunotherapy in lung adenocarcinoma

T Xie, G Fan, L Huang, N Lou, X Han, P Xing, Y Shi - Epigenomics, 2022 - Future Medicine
Aim: To find biomarkers for immunity and immunotherapy in lung adenocarcinoma (LUAD)
through multiomics analysis. Materials & methods: The multiomics data of patients with …

[HTML][HTML] Molecular markers that predict response to combined radiotherapy and immunotherapy in patients with lung adenocarcinoma: a bioinformatics analysis

L Sun, H Zhou, C Wu, Y Peng - Translational Cancer Research, 2023 - ncbi.nlm.nih.gov
Background Immunotherapy has had a high success rate in treating lung adenocarcinoma
(LUAD) for several decades. However, many patients do not benefit from immunotherapy …