Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that
hypertension is the result of many factors that interact to raise blood pressure and cause end …

Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …

Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …

The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Adipose tissue (AT) dysfunction, characterized by loss of its homeostatic functions, is a
hallmark of non-communicable diseases. It is characterized by chronic low-grade …

High blood pressure is present in more than one billion adults worldwide and is the most
important modifiable risk factor of death resulting from cardiovascular disease. While many …

Although systemic hypertension affects a large proportion of the population, its etiology
remains poorly defined. Emerging evidence supports the concept that immune cells become …

A diet rich in salt is linked to an increased risk of cerebrovascular diseases and dementia,
but it remains unclear how dietary salt harms the brain. We report that, in mice, excess …

Hypertension is a complex condition and is the most common cardiovascular risk factor,
contributing to widespread morbidity and mortality. Approximately 90% of hypertension …