Bradykinesia is one of the cardinal motor symptoms of Parkinson's disease and other
parkinsonisms. The various clinical aspects related to bradykinesia and the …

In Parkinson's disease, the progressive neurodegeneration of nigrostriatal dopaminergic
neurons in the substantia nigra pars compacta (SNc) is associated with classic motor …

In patients with Parkinson's disease, beta (β) and gamma (γ) oscillations are altered in the
basal ganglia, and this abnormality contributes to the pathophysiology of bradykinesia …

Beta-band activity in the subthalamic local field potential (LFP) is correlated with Parkinson's
disease (PD) symptom severity and is the therapeutic target of deep brain stimulation (DBS) …

The globus pallidus externa (GPe) functions as a central hub in the basal ganglia for
processing motor and non-motor information through the creation of complex connections …

Synchronized oscillations within and between brain areas facilitate normal processing, but
are often amplified in disease. A prominent example is the abnormally sustained beta …

Beta frequency oscillations (15 to 35 Hz) in cortical and basal ganglia circuits become
abnormally synchronized in Parkinson's disease (PD). How excessive beta oscillations …

The dynamical properties of cortico-basal ganglia (CBG) circuits are dramatically altered
following the loss of dopamine in Parkinson's disease (PD). The neural circuit dysfunctions …

The purpose of this review is to bridge the gap between earlier literature on striatal
cholinergic interneurons and mechanisms of microcircuit interaction demonstrated with the …

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is highly effective in
alleviating movement disability in patients with Parkinson's disease (PD). However, its …