[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Recent advances of smart materials for ocular drug delivery

X Wang, F Luan, H Yue, C Song, S Wang… - Advanced drug delivery …, 2023 - Elsevier
Owing to the variety and complexity of ocular diseases and the natural ocular barriers, drug
therapy for ocular diseases has significant limitations, such as poor drug targeting to the site …

Recent advances in waste-recycled nanomaterials for biomedical applications: Waste-to-wealth

M Abd Elkodous, HM El-Husseiny… - Nanotechnology …, 2021 - degruyter.com
Global overpopulation, industrial expansion, and urbanization have generated massive
amounts of wastes. This is considered as a significant worldwide challenge that requires an …

Liquid metals: preparation, surface engineering, and biomedical applications

N Yang, F Gong, Y Zhou, Q Yu, L Cheng - Coordination Chemistry Reviews, 2022 - Elsevier
Liquid metals (LMs) with high thermal/electrical conductivity, extraordinary fluidity, and
excellent biocompatibility have garnered considerable attention in the last decade …

Design, preparation, and functionalization of nanobiomaterials for enhanced efficacy in current and future biomedical applications

P Ramburrun, RA Khan, YE Choonara - Nanotechnology Reviews, 2022 - degruyter.com
Biocompatible, attuned, and congruent stimuli-responsive polymers of synthetic and plants
and animals-based origins are essential raw materials for constructing bio-matching …

Biophilic positive carbon dot exerts antifungal activity and augments corneal permeation for fungal keratitis

H Chen, X Geng, Q Ning, L Shi, N Zhang, S He… - Nano Letters, 2024 - ACS Publications
Fungal keratitis (FK) is an infectious eye disease that poses a significant risk of blindness.
However, the effectiveness of conventional antifungal drugs is limited due to the intrinsic …

Lactylation-driven FTO targets CDK2 to aggravate microvascular anomalies in diabetic retinopathy

X Chen, Y Wang, JN Wang, YC Zhang… - EMBO Molecular …, 2024 - embopress.org
Diabetic retinopathy (DR) is a leading cause of irreversible vision loss in working-age
populations. Fat mass and obesity-associated protein (FTO) is an N6-methyladenosine …

Microfluidic synthesis of ultrasmall chitosan/graphene quantum dots particles for intranasal delivery in Alzheimer's disease treatment

F Mohebichamkhorami, M Faizi, M Mahmoudifard… - Small, 2023 - Wiley Online Library
Nanoparticles (NPs) based therapies for Alzheimer's disease (AD) attract interest due to
their ability to pass across or bypass the blood‐brain barrier. Chitosan (CS) NPs or …

Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress

Y Shen, J Sun, X Sun - Journal of Nanobiotechnology, 2023 - Springer
Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over
76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040 …

Anti-oxidative and mucin-compensating dual-functional nano eye drops for synergistic treatment of dry eye disease

K Jin, Y Ge, Z Ye, X Pan, Y Yan, Z Mao, J Ye - Applied Materials Today, 2022 - Elsevier
Oxidative stress plays a central role in dry eye disease (DED), which can destroy the mucin
layer on the ocular surface. The currently available eye drops are palliative and short-lived …