Introduction: One of the possibilities for reducing the emergence and spread of antibiotic
resistance is the use of anti-resistance compounds capable of resensitizing resistant …

As a part of our drug discovery program, ursolic acid was chemically transformed into six
semi‐synthetic derivatives, which were evaluated for their antibacterial and drug resistance …

Multidrug resistance (MDR) put an alarming situation like preantibiotic era which compels us
to invigorate the basic science of anti-infective chemotherapy. Hence, the drug resistant …

Cancer is one of the most feared and dreaded diseases across the world. In clinical practice,
a variety of anticancer agents of natural, semi-synthetic and synthetic origin exist, but they …

Drug efflux pumps confer multidrug resistance to dangerous pathogens which makes these
pumps important drug targets. We have synthesised a novel series of compounds based on …

We explored the antibacterial potential (alone and combination) against multidrug resistant
(MDR) Pseudomonas aeruginosa isolates KG-P2 using synthesized thieno [3, 2-c] pyran-2 …

Abstract Treatment to common bacterial infections are becoming ineffective of late, owing to
the emergence and dissemination of antibiotic resistance globally. Escherichia coli and …

The tetralone and tetralone derivatives, as crucial structural scaffolds of potential novel
drugs targeted at multiple biological end-points, are normally found in several natural …

Antibiotic resistance is one of the most pressing health issues of our days. It can arise due to
a multiplicity of factors, such as target modification, decrease in the drug uptake, changes in …

Background Acinetobacter baumannii is an opportunistic pathogen that causes nosocomial
infections especially in patients in intensive care units (ICUs). Accordingly, the aim of our …