Tetralone scaffolds and their potential therapeutic applications

B Gauni, K Mehariya, A Shah… - Letters in Drug Design …, 2021 - ingentaconnect.com
Substituted tetralones have played a substantial role in organic synthesis due to their strong
reactivity and suitability as a starting material for a range of synthetic heterocyclic …

Comparative drug resistance reversal potential of natural glycosides: Potential of synergy niaziridin & niazirin

GR Dwivedi, A Maurya, DK Yadav… - Current Topics in …, 2019 - ingentaconnect.com
Background: Due to the limited availability of antibiotics, Gram-negative bacteria (GNB)
acquire different levels of drug resistance. It raised an urgent need to identify such agents …

In vitro, in vivo and in silico antihyperglycemic activity of some semi-synthetic phytol derivatives

HC Upadhyay, A Mishra, J Pandey… - Medicinal …, 2022 - ingentaconnect.com
Background: Due to the prevalence of type-2 diabetes across the globe, there is an unmet
need to explore new molecular targets for the development of cost-effective and safer …

[PDF][PDF] 逆转细菌耐药性研究进展

廖燕科, 蓝素桂, 苏爱秋, 彭燕鸿, 谭强 - 中国抗生素杂志, 2023 - zgkss.com.cn
逆转细菌耐药性研究进展 Page 1 . 32 . 收稿日期:2021-12-02 基金项目:广西区自然资金项目(No.
2014GXNSFAA118176) 作者简介:廖燕科,女,生于1996年,在读硕士研究生,主要研究方向为药物新 …

Multidrug efflux pumps and their inhibitors characterized by computational modeling

VK Ramaswamy, P Cacciotto, G Malloci… - … resistance in bacteria …, 2016 - Springer
Antimicrobial resistance is a key public health concern of our era due to an ever-increasing
number of drug-resistant pathogens, including several Gram-negative bacilli. The latter are …

Bio‐fabrication of Silver Nanoparticles Using Alysicarpus vaginalis Extract: Preparation, Characterization and Comparative in vitro Antibacterial Evaluations

KN Mishra, D Mohapatra, P Chaubey, AN Sahu… - …, 2023 - Wiley Online Library
Green synthesis of silver nanoparticles (AgNPs) using the Alysicarpus vaginalis alcoholic
extract as a reducing agent and a capping ligand was carried out. Notable peaks of λmax …

Synergistic antibacterial activity of gallic acid based chalcone Indl 2 by inhibiting efflux pump transporters

GR Dwivedi, N Pathak, N Tiwari, AS Negi… - Chemistry & …, 2024 - Wiley Online Library
As a part of novel discovery of drugs from natural resources, present study was undertaken
to explore the antibacterial potential of chalcone Indl‐2 in combination with different group of …

[HTML][HTML] Do South African medicinal plants used traditionally to treat infections respond differently to resistant microbial strains?

S Van Vuuren, T Muhlarhi - South African Journal of Botany, 2017 - Elsevier
Currently antimicrobial resistance is increasing at an alarming rate. Exposure to resistant
strains hinders treatment outcomes both in rural and hospital settings. Thus, the aim of this …

Design, synthesis and drug resistance reversal potential of novel curcumin mimics Van D: synergy potential of curcumin mimics

GR Dwivedi, S Khwaja, AS Negi, SS Panda… - Bioorganic …, 2021 - Elsevier
Being crucial part of plant-based novel discovery of drug from natural resources, a study was
done to explore the antibacterial potential of curcumin mimics in combination with antibiotics …

[PDF][PDF] Efflux pumps: warheads of gram-negative bacteria and efflux pump inhibitors

GR Dwivedi, DP Singh, SA Sharma… - New approaches in …, 2017 - researchgate.net
Among all the pathogenic bacteria, Gram-negative bacteria (GNB) are one of the major
causative agents of the hospital-acquired infections especially in cases of ventilator …