Targeting drugs to tumours using cell membrane-coated nanoparticles

RH Fang, W Gao, L Zhang - Nature Reviews Clinical Oncology, 2023 - nature.com
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …

[HTML][HTML] Liposomes: Structure, composition, types, and clinical applications

H Nsairat, D Khater, U Sayed, F Odeh, A Al Bawab… - Heliyon, 2022 - cell.com
Liposomes are now considered the most commonly used nanocarriers for various potentially
active hydrophobic and hydrophilic molecules due to their high biocompatibility …

[HTML][HTML] Nanoparticles as drug delivery systems: a review of the implication of nanoparticles' physicochemical properties on responses in biological systems

A Yusuf, ARZ Almotairy, H Henidi, OY Alshehri… - Polymers, 2023 - mdpi.com
In the last four decades, nanotechnology has gained momentum with no sign of slowing
down. The application of inventions or products from nanotechnology has revolutionised all …

[HTML][HTML] Drug delivery systems for RNA therapeutics

K Paunovska, D Loughrey, JE Dahlman - Nature Reviews Genetics, 2022 - nature.com
RNA-based gene therapy requires therapeutic RNA to function inside target cells without
eliciting unwanted immune responses. RNA can be ferried into cells using non-viral drug …

[HTML][HTML] A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics

RNL Lamptey, B Chaulagain, R Trivedi… - International journal of …, 2022 - mdpi.com
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …

[HTML][HTML] Review on metal nanoparticles as nanocarriers: Current challenges and perspectives in drug delivery systems

V Chandrakala, V Aruna, G Angajala - Emergent Materials, 2022 - Springer
Over the past few years, nanotechnology has been attracting considerable research
attention because of their outstanding mechanical, electromagnetic and optical properties …

[PDF][PDF] RETRACTED: Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol

P Nakhaei, R Margiana, DO Bokov… - … in bioengineering and …, 2021 - frontiersin.org
Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a
hydrophilic head constituting a phospholipid membrane. The spherical or multilayered …

To PEGylate or not to PEGylate: Immunological properties of nanomedicine's most popular component, polyethylene glycol and its alternatives

D Shi, D Beasock, A Fessler, J Szebeni… - Advanced drug delivery …, 2022 - Elsevier
Polyethylene glycol or PEG has a long history of use in medicine. Many conventional
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …

The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives

R Sun, J Xiang, Q Zhou, Y Piao, J Tang, S Shao… - Advanced Drug Delivery …, 2022 - Elsevier
Over the past three decades, the enhanced permeability and retention (EPR) effect has
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …

Nanotechnology-based mRNA vaccines

S Chen, X Huang, Y Xue, E Álvarez-Benedicto… - Nature Reviews …, 2023 - nature.com
Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …