Compulsion is a cardinal symptom of drug addiction (severe substance use disorder).
However, compulsion is observed in only a small proportion of individuals who repeatedly …

The impaired response inhibition and salience attribution (iRISA) model proposes that
impaired response inhibition and salience attribution underlie drug seeking and taking. To …

Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …

Androgens are potent drugs requiring prescription for valid medical indications but are
misused for invalid, unproven, or off-label reasons as well as being abused without …

As evidenced through classic Pavlovian learning mechanisms, environmental cues can
become incentivized and influence behavior. These stimulus-outcome associations are …

Addiction is a disease characterized by compulsive drug seeking and consumption
observed in 20–30% of users. An addicted individual will favor drug reward over natural …

Background Substance use disorders (SUD) are a category of psychiatric disorders with a
large epidemiological and societal impact around the world. In the last decades, a large …

Impulse control is becoming a critical survival skill for the twenty-first century. Impulsivity is
implicated in virtually all externalizing behaviours and disorders, and figures prominently in …

Alcohol abuse and alcohol dependence are key factors in the development of alcohol use
disorder, which is a pervasive societal problem with substantial economic, medical, and …

Behavioral neuroscience research incorporates the identical high level of meticulous
methodologies and exacting attention to detail as all other scientific disciplines. To achieve …