Inflammatory bowel disease (IBD) is a chronic, relapsing gastrointestinal (GI) disorder
characterized by intestinal inflammation. The etiology of IBD is multifactorial and results from …

Pulmonary fibrosis is an enduring and advancing pulmonary interstitial disease caused by
multiple factors that ultimately lead to structural changes in normal lung tissue. Currently …

Background A growing body of research shows that drug monomers from traditional
Chinese herbal medicines have antineuroinflammatory and neuroprotective effects that can …

Osteoarthritis is non-inflammatory degenerative joint arthritis, which exacerbates disability in
elder persons. The molecular mechanisms of osteoarthritis are elusive. Ubiquitination, one …

Osteoporosis, a systemic bone disease that is characterized by a reduction in bone mass
and destruction of bone microstructure, is becoming a serious problem worldwide. Bone …

The rhizomes of Polygonatum sibiricum are commonly consumed as food and also used as
medicine. However, the metabolic profile of P. sibiricum has not been fully revealed yet …

The active substances derived from plants have received increasing attention owing to their
wide range of pharmacological applications, including anti-tumor, anti-allergic, anti-viral …

Ulcerative colitis (UC) is an inflammatory bowel disease generally characterized by chronic,
persistent, recurrent, and non-specific ulcers of the intestine. Its main clinical manifestations …

Hepatic fibrosis is the formation of scar tissue in the liver. This scar tissue replaces healthy
liver tissue and can lead to liver dysfunction and failure if left untreated. It is usually caused …

Striking progress is being made in cancer treatment by using small molecule inhibitors of
specific protein kinases that are products of genes recognized as drivers for a specific type …