Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

Over the past 10 years, circulating tumor cells (CTC) and circulating tumor DNA (ctDNA)
have received enormous attention as new biomarkers and subjects of translational research …

Metastasis formation is the main cause of cancer-related death in patients with solid
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …

Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Cancer-related deaths are mainly caused by metastatic spread of tumor cells from the
primary lesion to distant sites via the blood circulation. Understanding the mechanisms of …

The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …

The circulating tumor cells (CTCs, the root cause of cancer metastasis and poor cancer
prognosis) are very difficult to culture for scale-up in vitro, which has hampered their use in …

Background In non-small cell lung cancer (NSCLC), analysis of programmed cell death
ligand 1 (PD-L1) expression in circulating tumor cells (CTCs) is a potential alternative to …

Circulating tumor cells (CTCs) are released from primary tumors and transported through the
body via blood or lymphatic vessels before settling to form micrometastases under suitable …

Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein expressed in
epithelial tissues. EpCAM forms intercellular, homophilic adhesions, modulates epithelial …