Nanotechnology has recently gained increased attention for its capability to effectively
diagnose and treat various tumors. Nanocarriers have been used to circumvent the …

This paper describes the substances of plant and marine origin that have anticancer
properties. The chemical structure of the molecules of these substances, their properties …

Purpose: An anti-HER2 antibody–drug conjugate with a novel topoisomerase I inhibitor, DS-
8201a, was generated as a new antitumor drug candidate, and its preclinical pharmacologic …

Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

Background In a phase 1–2 trial of albumin-bound paclitaxel (nab-paclitaxel) plus
gemcitabine, substantial clinical activity was noted in patients with advanced pancreatic …

Background: Positive findings from the phase III MPACT trial led to the regulatory approval of
nab-paclitaxel plus gemcitabine as a treatment option for patients with metastatic pancreatic …

Pancreatic cancer is expected to be the second deadliest malignancy in the USA by 2020.
The survival rates for patients with other gastrointestinal malignancies have increased …

Answer questions and earn CME/CNE Pancreatic cancer is currently one of the deadliest of
the solid malignancies. However, surgery to resect neoplasms of the pancreas is safer and …

Purpose To provide evidence-based recommendations to oncologists and others for the
treatment of patients with metastatic pancreatic cancer. Methods American Society of …

Pancreatic ductal adenocarcinoma (PDA) is an almost uniformly lethal disease. One
explanation for the devastating prognosis is the failure of many chemotherapies, including …