Recent development of visceral leishmaniasis treatments: successes, pitfalls, and perspectives

F Alves, G Bilbe, S Blesson, V Goyal… - Clinical microbiology …, 2018 - Am Soc Microbiol
Research in visceral leishmaniasis in the last decade has been focused on how better to
use the existing medicines as monotherapy or in combination. Systematic research by …

[HTML][HTML] Visceral leishmaniasis: a global overview

RG Wamai, J Kahn, J McGloin, G Ziaggi - Journal of Global Health …, 2020 - e-jghs.org
The leishmaniases are protozoan infections that are among the neglected tropical diseases
(NTDs). Over one billion people are at risk of these diseases in virtually all continents. These …

The burden of neglected tropical diseases in Brazil, 1990-2016: a subnational analysis from the Global Burden of Disease Study 2016

FR Martins-Melo, M Carneiro… - PLoS neglected …, 2018 - journals.plos.org
Background Neglected Tropical Diseases (NTDs) are important causes of morbidity,
disability, and mortality among poor and vulnerable populations in several countries …

[HTML][HTML] Mortality from neglected tropical diseases in Brazil, 2000–2011

FR Martins-Melo, AN Ramos Jr… - Bulletin of the World …, 2016 - ncbi.nlm.nih.gov
Methods We extracted information on cause of death, age, sex, ethnicity and place of
residence from the nationwide mortality information system at the Brazilian Ministry of …

Burden of leishmaniasis in Brazil and federated units, 1990-2016: Findings from Global Burden of Disease Study 2016

JMT Bezerra, VEM de Araújo, DS Barbosa… - PLoS neglected …, 2018 - journals.plos.org
Background The study presents estimates for the burden of visceral leishmaniasis (VL) and
cutaneous and mucocutaneous leishmaniasis (CML) in Brazil and its 27 federated units …

Same parasite, different outcomes: unraveling the epidemiology of Leishmania infantum infection in Brazil and Spain

T de Freitas Milagres, M López-de-Felipe… - Trends in …, 2023 - cell.com
Human leishmaniosis caused by Leishmania infantum is an important health problem
worldwide. One of the main aspects arousing interest is the epidemiological scenario …

[HTML][HTML] Changes in the epidemiology of visceral leishmaniasis in Brazil from 2001 to 2014

LL Reis, AAS Balieiro, FR Fonseca… - Revista da Sociedade …, 2017 - SciELO Brasil
INTRODUCTION Visceral leishmaniasis (VL) is a neglected disease, with territorial
expansion and regional differences in Brazil that require explanation. This study aimed to …

Sex‐Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species

RD Lockard, ME Wilson… - Journal of immunology …, 2019 - Wiley Online Library
Worldwide, an estimated 12 million people are infected with Leishmania spp. and an
additional 350 million are at risk of infection. Leishmania are intracellular parasites that …

A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

JBT Carnielli, K Crouch, S Forrester, VC Silva… - …, 2018 - thelancet.com
Background Miltefosine has been used successfully to treat visceral leishmaniasis (VL) in
India, but it was unsuccessful for VL in a clinical trial in Brazil. Methods To identify molecular …

Leishmaniasis beyond east Africa

CM Jones, SC Welburn - Frontiers in Veterinary Science, 2021 - frontiersin.org
Climate change is having a substantial impact on our environment and ecosystems and has
altered the way humans live, access, and utilize resources with increased risk of zoonotic …