Hepatocellular carcinoma treatment: hurdles, advances and prospects

R Kumari, MK Sahu, A Tripathy, K Uthansingh… - Hepatic …, 2018 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related mortality and
is particularly refractory to the available chemotherapeutic drugs. Among various etiologies …

Role of endoglin (CD105) in the progression of hepatocellular carcinoma and anti-angiogenic therapy

A Kasprzak, A Adamek - International Journal of Molecular Sciences, 2018 - mdpi.com
The liver is perfused by both arterial and venous blood, with a resulting abnormal
microenvironment selecting for more-aggressive malignancies. Hepatocellular carcinoma …

Expected and Unexpected Imaging Findings after 90Y Transarterial Radioembolization for Liver Tumors

JC Spina, I Hume, A Pelaez, O Peralta, M Quadrelli… - Radiographics, 2019 - pubs.rsna.org
Transarterial radioembolization (TARE), also called radioembolization or selective internal
radiation therapy, is an interventional radiology technique used to treat primary liver tumors …

Tumor treating fields concomitant with sorafenib in advanced hepatocellular cancer: Results of the HEPANOVA phase II study

E Gkika, AL Grosu, T Macarulla Mercade… - Cancers, 2022 - mdpi.com
Simple Summary Advanced hepatocellular carcinoma (HCC) is an aggressive liver cancer
with limited treatment options and poor prognosis. Tumor-Treating Fields (TTFields) are …

Role of virus-related chronic inflammation and mechanisms of cancer immune-suppression in pathogenesis and progression of hepatocellular carcinoma

M Borgia, M Dal Bo, G Toffoli - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma pathogenesis is dependent on a chronic
inflammation caused by several factors, including hepatotropic viruses, such as HCV and …

Highly tumor-specific and long-acting iodine-131 microbeads for enhanced treatment of hepatocellular carcinoma with low-dose radio-chemoembolization

Y Qian, Q Liu, P Li, Y Han, J Zhang, J Xu, J Sun, A Wu… - ACS …, 2021 - ACS Publications
Transarterial radioembolization (TARE) is considered the standard treatment for
intermediate-stage hepatocellular carcinoma (HCC). Iodine-131 (131I)-labeled lipiodol …

Hyaluronic acid/doxorubicin nanoassembly-releasing microspheres for the transarterial chemoembolization of a liver tumor

SY Lee, JW Choi, JY Lee, DD Kim, HC Kim, HJ Cho - Drug delivery, 2018 - Taylor & Francis
Abstract Doxorubicin (DOX)-loaded, hyaluronic acid-ceramide (HACE) nanoassembly-
releasing poly (lactic-co-glycolic acid)(PLGA) microspheres (MSs) were developed for …

Microspheres as a carrier system for therapeutic embolization procedures: Achievements and advances

MM Welling, N Duszenko, MP van Meerbeek… - Journal of Clinical …, 2023 - mdpi.com
The targeted delivery of anti-cancer drugs and isotopes is one of the most pursued goals in
anti-cancer therapy. One of the prime examples of such an application is the intra-arterial …

[HTML][HTML] Radioembolization for hepatocellular carcinoma: what clinicians need to know

JW Choi, HC Kim - Journal of Liver Cancer, 2022 - synapse.koreamed.org
Transarterial radioembolization (TARE) with yttrium 90 (90 Y) has been used in the
management of hepatocellular carcinoma (HCC) for more than 10 years in Korea. There are …

[HTML][HTML] The modified Response Evaluation Criteria in Solid Tumors (RECIST) yield a more accurate prognoses than the RECIST 1.1 in hepatocellular carcinoma …

JS Lee, HJ Choi, BK Kim, JY Park, SH Ahn, KH Han… - Gut and liver, 2020 - ncbi.nlm.nih.gov
Methods In total, 102 patients with unresectable intrahepatic HCC, who were treated with
TARE between 2012 and 2017, were reviewed retrospectively. The treatment response after …