With the development of a new generation of hydroxyethyl starches (HES), there has been
renewed interest in their clinical potential. High doses of first-and second-generation HES …

METHODS We used a formal search strategy to assess the safety of tetrastarches when
used during surgery. We decided a priori to include in our evaluation data only from …

Hydroxyethyl starch has recently become the subject of renewed interest because of the
introduction of a new specification, hydroxyethyl starch 130/0.4, as well as the clinical …

BACKGROUND: Hydroxyethyl starches (HES) are widely used for intravascular volume
therapy in surgical, emergency, and intensive care patients. There are safety concerns with …

Despite evidence from clinical studies and meta-analyses that resuscitation with colloids or
crystalloids is equally effective in critically ill patients, and despite reports from high-quality …

Background The purpose of this study was to test the equivalence of efficacy and compare
the safety of the 6% hydroxyethyl starches (HES) Voluven (HES 130/0.4; Fresenius Kabi …

Hydroxyethyl starch (HES) is widely used for fluid management in broad populations of
patients, particularly in the surgery and intensive care settings. Pruritus, often manifested as …

IMPLICATIONS: By using a MEDLINE search covering the last 3 yr, the present knowledge
on volume replacement regimens was analyzed. Forty studies in humans were identified …

Background. The volume expansion effect of a recently introduced hydroxyethyl starch, HES
130/0.4, was compared with the commonly used HES 200/0.5 after rapid infusion of a single …

Hydroxyethyl starch (HES) is a widely used plasma substitute for correcting perioperative
hypovolemia. HES preparations are defined by concentration, molar substitution (MS), mean …