Pathways involved in testicular germ cell apoptosis in immature rats after FSH suppression

SM Ruwanpura, RI McLachlan… - Journal of …, 2008 - joe.bioscientifica.com
The anterior pituitary is active mitotically and apoptotically under basal conditions and in
response to a variety of physiological and pathophysiological stimuli. Hypothyroidism in man …

Defects in the regulatory clearance mechanisms favor the breakdown of self-tolerance during spontaneous autoimmune orchitis

RM Pelletier, SR Yoon, CD Akpovi… - American Journal of …, 2009 - journals.physiology.org
We identified aberrations leading to spontaneous autoimmune orchitis (AIO) in mink, a
seasonal breeder and natural model for autoimmunity. This study provides evidence …

Proliferation and apoptosis in aged and photoregressed mammalian seminiferous epithelium, with particular attention to rodents and humans

LM Pastor, A Zuasti, C Ferrer… - … in domestic animals, 2011 - Wiley Online Library
Contents Imbalances in the proliferation and apoptosis processes are involved in numerous
epithelial alterations. In the seminiferous epithelium, normal spermatogenesis is regulated …

Effects of a mixture of low doses of atrazine and benzo [a] pyrene on the rat seminiferous epithelium either during or after the establishment of the blood-testis barrier …

P Durand, A Blondet, G Martin, D Carette, G Pointis… - Toxicology in Vitro, 2020 - Elsevier
Atrazine (ATZ), a widely used agricultural pesticide and benzo [a] pyrene (BaP), a ubiquitous
environmental human carcinogen can induce alterations of spermatogenesis. In the present …

Follicle-stimulating hormone affects spermatogonial survival by regulating the intrinsic apoptotic pathway in adult rats

SM Ruwanpura, RI McLachlan, PG Stanton… - Biology of …, 2008 - academic.oup.com
Follicle-stimulating hormone plays a key role in spermatogonial development in adult rats
via poorly understood mechanisms. We aimed to identify the role of this hormone in the …

Effects of low doses of carbendazim or iprodione either separately or in mixture on the pubertal rat seminiferous epithelium: An ex vivo study

P Durand, G Martin, A Blondet, J Gilleron, D Carette… - Toxicology in Vitro, 2017 - Elsevier
It has been shown that non-cytotoxic doses of Carbendazim (CBZ), a broad-spectrum
benzimidazole fungicide, possess endocrine-disrupting (androgen-like) actions, ex vivo, on …

The DNA damage checkpoint protein RAD9A is essential for male meiosis in the mouse

A Vasileva, KM Hopkins, X Wang… - Journal of cell …, 2013 - journals.biologists.com
In mitotic cells, RAD9A functions in repairing DNA double-strand breaks (DSBs) by
homologous recombination and facilitates the process by cell cycle checkpoint control in …

Stress and testicular germ cell apoptosis

I Sasagawa, H Yazawa, Y Suzuki… - Archives of andrology, 2001 - Taylor & Francis
Chronic immobilization stress provokes an increase in serum corticosterone, which causes
the decline in testosterone concentration. The stress and glucocorticoid administration …

Induction of male germ cell apoptosis by testosterone withdrawal after ethane dimethanesulfonate treatment in adult rats.

M Bakalska, N Atanassova, Y Koeva, B Nikolov… - Endocrine …, 2004 - europepmc.org
Objective To carry out a detailed quantitative analysis of male germ cell apoptosis in
seminiferous epithelium in a long period after EDS administration. Methods The apoptosis in …

The Fas system in the seminiferous epithelium and its possible extra‐testicular role

A Riccioli, L Salvati, A D'Alessio, D Starace… - Andrologia, 2003 - Wiley Online Library
The Fas system is involved in the control of immune system homeostasis and nonfunctional
Fas system leads to autoimmune disease in mice and humans. The Fas system is a …