Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a recently defined entity
that includes rare kidney diseases characterized by tubular damage and interstitial fibrosis …

Uromodulin (also known as Tamm-Horsfall protein) is exclusively produced in the kidney
and is the most abundant protein in normal urine. The function of uromodulin remains …

INTRODUCTION Acute kidney injury and chronic kidney disease (CKD) are common in
hospitalized patients. To inform clinical decision making, more accurate information …

Uromodulin, a protein exclusively produced by the kidney, is the most abundant urinary
protein in physiological conditions. Already described several decades ago, uromodulin has …

Pseudomonas aeruginosa can cause complicated urinary tract infections, particularly in
people with catheters, which can lead to pyelonephritis. Whilst some subgroups appear …

Differences in health status by socioeconomic position (SEP) tend to be more evident at
older ages, suggesting the involvement of a biological mechanism responsive to the …

Autosomal dominant tubulointerstitial kidney disease (ADTKD) is an increasingly recognized
cause of end-stage kidney disease, primarily due to mutations in UMOD and MUC1. The …

Background An ELISA to analyse uromodulin in human serum (sUmod) was developed,
validated and tested for clinical applications. Methods We assessed sUmod, a very stable …

Deficiency of the micronutrient zinc is common in patients with chronic kidney disease
(CKD). The aim of this review is to summarize evidence presented in literature for …

Uromodulin, the most abundant protein in normal urine, is essentially produced by the cells
lining the thick ascending limb. There it regulates the activity of the cotransporter NKCC2 …