Blood pressure targets in patients with coronary artery disease: observations from traditional and Bayesian random effects meta-analysis of randomised trials

S Bangalore, S Kumar, A Volodarskiy, FH Messerli - Heart, 2013 - heart.bmj.com
Context Most guidelines for treatment of hypertension including the Joint National
Committee-7 recommend a blood pressure (BP) goal of< 140/90 mm Hg for hypertensive …

Metabolic syndrome: treatment of hypertensive patients

ZH Israili, B Lyoussi… - American journal of …, 2007 - journals.lww.com
Metabolic syndrome (MetSyndr), a constellation of abnormalities [obesity, glucose
intolerance, insulin resistance (IR), dyslipidemia (low HDL-cholesterol, high LDL-cholesterol …

Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial

G Mancia, G Parati, M Revera, G Bilo, A Giuliano… - BMJ, 2010 - bmj.com
Objective To investigate the possibility that statins reduce blood pressure as well as
cholesterol concentrations through clinic and 24 hour ambulatory blood pressure …

Effects of atorvastatin, amlodipine, and their combination on vascular dysfunction in insulin-resistant rats

T Okamura, M Tawa, A Geddawy… - Journal of …, 2014 - jstage.jst.go.jp
Deficiency of tetrahydrobiopterin (BH4) in the vascular tissue contributes to endothelial
dysfunction through reduced eNOS activity and increased superoxide anion (O2−) …

Combination therapy of amlodipine and atorvastatin has more beneficial vascular effects than monotherapy in salt-sensitive hypertension

MS Zhou, R Tian, EA Jaimes… - American journal of …, 2014 - academic.oup.com
BACKGROUND Current treatment for the secondary prevention of cardiovascular diseases
frequently involves the prescription of several combination therapies, particularly …

Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? Rationale and design for an …

FDR Hobbs, G Gensini, GBJ Mancini… - International journal of …, 2006 - Elsevier
BACKGROUND: In order to prevent cardiovascular events, it is essential to effectively
manage overall risk of cardiovascular disease. However, despite guideline …

Development of a RP-HPLC method for the simultaneous analysis of diltiazem and statin: Application in pharmaceuticals and human serum

N Sultana, MS Arayne, N Shafi, FA Siddiqui… - Analytical …, 2010 - pubs.rsc.org
High-performance liquid chromatographic (HPLC) method has been developed and
validated for the simultaneous determination of diltiazem and statins in raw materials, their …

Modulation of arterial reactivity using amlodipine and atorvastatin measured by ultrasound examination (MARGAUX)

F Charbonneau, TJ Anderson, L Title, J Jobin, P Poirier… - Atherosclerosis, 2008 - Elsevier
OBJECTIVE: To evaluate the effect of the calcium channel blocker amlodipine on
endothelial function in normotensive patients with coronary disease taking concomitant …

Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints

SA Doggrell - Reviews on recent clinical trials, 2006 - ingentaconnect.com
Placebo-controlled clinical trials have shown that atorvastatin is beneficial in patients with
myocardial ischemia, established coronary artery disease, hypertension and 3 other …

A single-pill combination of amlodipine besylate and atorvastatin calcium.

R Blank - Drugs of Today (Barcelona, Spain: 1998), 2006 - europepmc.org
This review describes the clinical profile and rationale for the development of a single-pill
formulation of the calcium channel blocker amlodipine besylate, a blood pressure-lowering …