The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …
[HTML][HTML] In vitro Label Free Raman Microspectroscopic Analysis to Monitor the Uptake, Fate and Impacts of Nanoparticle Based Materials
The continued emergence of nanoscale materials for nanoparticle-based therapy, sensing
and imaging, as well as their more general adoption in a broad range of industrial …
and imaging, as well as their more general adoption in a broad range of industrial …
Exploiting blood transport proteins as carborane supramolecular vehicles for boron neutron capture therapy
Carboranes are promising agents for applications in boron neutron capture therapy (BNCT),
but their hydrophobicity prevents their use in physiological environments. Here, by using …
but their hydrophobicity prevents their use in physiological environments. Here, by using …
Metallodrugs against Breast Cancer: Combining the Tamoxifen Vector with Platinum (II) and Palladium (II) Complexes
A Kazimir, B Schwarze, P Lönnecke, S Jelača… - Pharmaceutics, 2023 - mdpi.com
The luminal A-subtype of breast cancer, where the oestrogen receptor α (ERα) is
overexpressed, is the most frequent one. The prodrug tamoxifen (1) is the clinically used …
overexpressed, is the most frequent one. The prodrug tamoxifen (1) is the clinically used …
Structural patterns enhancing the antibacterial activity of metallacarborane-based antibiotics
J Cebula, K Fink, W Goldeman… - Journal of Medicinal …, 2023 - ACS Publications
Healthcare systems heavily rely on antibiotics to treat bacterial infections, but the
widespread presence of multidrug-resistant bacteria puts this strategy in danger. Novel …
widespread presence of multidrug-resistant bacteria puts this strategy in danger. Novel …
Expanding the range of bioorthogonal tags for multiplex stimulated Raman scattering microscopy
N Murphy, WJ Tipping, HJ Braddick… - Angewandte …, 2023 - Wiley Online Library
Multiplex optical detection in live cells is challenging due to overlapping signals and poor
signal‐to‐noise associated with some chemical reporters. To address this, the application of …
signal‐to‐noise associated with some chemical reporters. To address this, the application of …
Bridging Smart Nanosystems with Clinically Relevant Models and Advanced Imaging for Precision Drug Delivery
Q Zhou, Q Liu, Y Wang, J Chen, O Schmid… - Advanced …, 2024 - Wiley Online Library
Intracellular delivery of nano‐drug‐carriers (NDC) to specific cells, diseased regions, or
solid tumors has entered the era of precision medicine that requires systematic knowledge …
solid tumors has entered the era of precision medicine that requires systematic knowledge …
Ruthenacarborane–phenanthroline derivatives as potential metallodrugs
M Kellert, I Sárosi, R Rajaratnam, E Meggers… - Molecules, 2020 - mdpi.com
Ruthenium-based complexes have received much interest as potential metallodrugs. In this
work, four RuII complexes bearing a dicarbollide moiety, a carbonyl ligand, and a …
work, four RuII complexes bearing a dicarbollide moiety, a carbonyl ligand, and a …
Radioactive Nano-and Microparticles Released from Fukushima Daiichi: Technical Challenges of Multiple Analytic Techniques
S Utsunomiya, K Fueda, K Minomo, K Horie… - 2022 - books.rsc.org
A total activity of∼ 10 19 Bq, including∼ 10 16 Bq of 137 Cs, was released from the
Fukushima Daiichi Nuclear Power Plant (FDNPP) in 2011, among which 137 Cs (30.1 years …
Fukushima Daiichi Nuclear Power Plant (FDNPP) in 2011, among which 137 Cs (30.1 years …
Dosimetry and Imaging of Micro and Nanoparticles by Means of High Resolution Techniques
T Venus, T Meyer, C Zilberfain, J Böttner, A Lampen… - 2022 - books.rsc.org
One of the most pressing issues nowadays is to control and reduce environmental pollution
produced by human activities through industrialization and urbanization. Apart from gaseous …
produced by human activities through industrialization and urbanization. Apart from gaseous …