The central metabolic role of ATP has stimulated much interest in how it is formed using the
energy from oxidations or light. Considerations based on analogy to ATP formation in the …

With the advent of technologies to obtain the complete sequence of the human genome in a
cost-effective manner, this decade and those to come will see an exponential increase in our …

MUSCLE contraction is driven by the cyclical interaction of myosin with actin, coupled to the
breakdown of ATP. Studies of the interaction of filamentous myosin1 and of a double …

Single actin filaments (∼ 7nm in diameter) labelled with fluorescent phalloidin can be
clearly seen by video-fluorescence microscopy1. This technique has been used to observe …

We have estimated the step size of the myosin cross-bridge (d, displacement of an actin
filament per one ATP hydrolysis) in an in vitro motility assay system by measuring the …

Molecular motors are protein machines whose directed movement along cytoskeletal
filaments is driven by ATP hydrolysis. Eukaryotic cells contain motors that help to transport …

▪ Abstract Myosin is a highly conserved, ubiquitous protein found in all eukaryotic cells,
where it provides the motor function for diverse movements such as cytokinesis …

The myosin head consists of a globular catalytic domain that binds actin and hydrolyzes ATP
and a neck domain that consists of essential and regulatory light chains bound to a long …

Publisher Summary One important result from in vitro studies of the interaction of the major
proteins of muscle, actin and myosin, has been the growing recognition that nearly any …

Fluorine is the thirteenth most abundant element in the earth's crust, but fluoride
concentrations in surface water are low and fluorinated metabolites are extremely rare,. The …