[HTML][HTML] High Bone Mass is associated with bone-forming features of osteoarthritis in non-weight bearing joints independent of body mass index

CL Gregson, SA Hardcastle, A Murphy, B Faber… - Bone, 2017 - Elsevier
Abstract Objectives High Bone Mass (HBM) is associated with (a) radiographic knee
osteoarthritis (OA), partly mediated by increased BMI, and (b) pelvic enthesophytes and hip …

Increased thymosin β4 levels in the serum and SF of knee osteoarthritis patients correlate with disease severity

M Wei, D Duan, Y Liu, Z Wang, Z Li - Regulatory Peptides, 2013 - Elsevier
Objective Thymosin β4, a member of a large family of thymic proteins, plays an important
role in the process of articular cartilage degeneration which is a common cause of …

Wnt10b and Dkk-1 gene therapy differentially influenced trabecular bone architecture, soft tissue integrity, and osteophytosis in a skeletally mature rat model of …

JB Mason, BL Gurda, KD Hankenson… - Connective Tissue …, 2017 - Taylor & Francis
Aims: Our goals in the current experiments were to determine if (a) upregulation of Wnt
signaling would induce osteoarthritis changes in stable stifle joints and (b) if downregulation …

A possible mechanism in DHEA-mediated protection against osteoarthritis

W Li, L Tang, Y Xiong, W Chen, X Zhou, Q Ding, L Wu - Steroids, 2014 - Elsevier
Dehydroepiandrosterone (DHEA) and its ester form, DHEA-S, are the most abundant
steroids in human plasma. Our previous studies showed that DHEA protects against …

[PDF][PDF] Association between hypoxia-inducible factor-1a levels in serum and synovial fluid with the radiographic severity of knee osteoarthritis

H Chu, ZM Xu, H Yu, KJ Zhu, H Huang - Genet Mol Res, 2014 - funpecrp.com.br
Osteoarthritis (OA) is primarily characterized by articular cartilage degradation. Hypoxia-
inducible factor-1a (HIF-1a), a subunit of the basic helix-loop-helix-containing PER-ARNT …

[PDF][PDF] Bone biomarkers related to osteoarthritis

M Engbersen, Z Huang, V Kraus - Biomarkers in disease: methods …, 2016 - researchgate.net
It is evident that the bone plays a vital role in osteoarthritis (OA) disease pathogenesis,
progression, and symptomatology. The close interaction of the bone and cartilage in the …

[引用][C] Dkk-1 蛋白的研究现状, 进展及临床意义

姜博, 廉永云 - 医学与哲学: B, 2012

[HTML][HTML] Human umbilical cord mesenchymal stem cells in combination with hyaluronic acid ameliorate the progression of knee osteoarthritis

JL Wu, PC Wong, CW Ho, CH Chen, KY Liao, R Lovel… - Applied Sciences, 2021 - mdpi.com
The aim of this study is to evaluate the feasibility and usefulness of the human umbilical cord
mesenchymal stem cells (hUC-MSCs) and hyaluronan acid (HA) combination to attenuate …

[HTML][HTML] Association of follistatin-like 3 concentrations in serum and synovial fluid with the radiographic severity of knee osteoarthritis

G Liu, S Chen, S Deng, X Ma, Y Hao… - International journal of …, 2015 - ncbi.nlm.nih.gov
Objective: Follistatin-like 3 (FSTL3), a circulating glycoprotein, is correlated with obesity and
inflammation, which are potential mechanisms of osteoarthritis (OA). This study aims to …

[引用][C] Dkk-1 干预对骨关节炎的治疗作用

熊健斌, 彭伟秋, 孙宏志 - 广西医科大学学报, 2014