Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach

M Aliyu, FT Zohora, AU Anka, K Ali, S Maleknia… - International …, 2022 - Elsevier
Several studies have shown that interleukin 6 (IL-6) is a multifunctional cytokine with both
pro-inflammatory and anti-inflammatory activity, depending on the immune response …

Skin pigmentation types, causes and treatment—a review

AM Thawabteh, A Jibreen, D Karaman, A Thawabteh… - Molecules, 2023 - mdpi.com
Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted
by genetics, UV exposure, and some drugs. Patients' physical appearance, psychological …

The mosaic of autoimmunity–Finally discussing in person. The 13th international congress on autoimmunity 2022 (AUTO13) Athens

N Mahroum, A Elsalti, A Alwani, I Seida, M Alrais… - Autoimmunity …, 2022 - Elsevier
While autoimmunity is a branch of medicine linked to every single organ system via direct
and indirect pathways, meeting in person to discuss autoimmunity during the 13 th …

Therapeutic potential of adipose tissue‐derivatives in modern dermatology

B Bellei, E Migliano, M Picardo - Experimental Dermatology, 2022 - Wiley Online Library
Stem cell‐mediated therapies in combination with biomaterial and growth factor‐based
approaches in regenerative medicine are rapidly evolving with increasing application …

Immunosuppressive nanoparticles containing recombinant PD-L1 and methotrexate alleviate multi-organ inflammation

EK An, W Zhang, HB Park, SJ Kim, HY Eom, J Hwang… - Biomaterials, 2023 - Elsevier
Multi-organ inflammatory diseases are one of the most serious autoimmune diseases
worldwide. The regulation of immune responses by immune checkpoint proteins influences …

Folic acid protects melanocytes from oxidative stress via activation of Nrf2 and inhibition of HMGB1

P Du, S Zhang, S Li, Y Yang, P Kang… - Oxidative Medicine …, 2021 - Wiley Online Library
Vitiligo is a cutaneous depigmentation disease due to loss of epidermal melanocytes.
Accumulating evidence has indicated that oxidative stress plays a vital role in vitiligo via …

Management of stable vitiligo—a review of the surgical approach

M Grochocka, A Wełniak, A Białczyk… - Journal of Clinical …, 2023 - mdpi.com
At present, vitiligo is the most common depigmenting skin disorder, characterized by clearly
demarcated discolored patches of various shapes and sizes. Depigmentation results from …

Silk Fibroin-Based Hydrogel Microneedles Deliver α-MSH to Promote Melanosome Delivery for Vitiligo Treatment

S Chong, C Wei, L Feng, R Guo - ACS Biomaterials Science & …, 2023 - ACS Publications
Microneedles have shown great advantages in subcutaneous drug delivery and skin
disease treatment. Vitiligo is a difficult-to-cure skin disease characterized by the …

[HTML][HTML] Efficacy and safety of natural Aloe Vera gel in the treatment of stable vitiligo

S Padmakar, GA Kumar, N Khurana, S Kumari… - … Epidemiology and Global …, 2023 - Elsevier
Background Vitiligo is a condition that causes a patchy loss of skin pigmentation. The Aloe
Vera plant has been used to treat a wide range of ailments, including skin diseases; …

Management of the refractory vitiligo patient: current therapeutic strategies and future options

X Wang, W Wu, J Chen, C Li, S Li - Frontiers in Immunology, 2024 - frontiersin.org
Vitiligo is an autoimmune disease that leads to disfiguring depigmented lesions of skin and
mucosa. Although effective treatments are available for vitiligo, there are still some patients …