Clinical update on head and neck cancer: molecular biology and ongoing challenges

E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli… - Cell death & …, 2019 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) are an aggressive, genetically
complex and difficult to treat group of cancers. In lieu of truly effective targeted therapies …

Somatic host cell alterations in HPV carcinogenesis

TR Litwin, MA Clarke, M Dean, N Wentzensen - Viruses, 2017 - mdpi.com
High-risk human papilloma virus (HPV) infections cause cancers in different organ sites,
most commonly cervical and head and neck cancers. While carcinogenesis is initiated by …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

Unraveling diverse roles of noncoding RNAs in various human papillomavirus negative cancers

X Chen, Y Liu, H Liu, Z Wang, X Zhu - Pharmacology & Therapeutics, 2022 - Elsevier
Human papillomavirus (HPV)-negative tumors distinguish from cancers associated with HPV
infection. Due to its high rate of lymph node metastasis and difficulty in inchoate discover …

Drug targeting and biomarkers in head and neck cancers: insights from systems biology analyses

T Islam, R Rahman, E Gov, B Turanli… - Omics: a journal of …, 2018 - liebertpub.com
The head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers
in the world, but robust biomarkers and diagnostics are still not available. This study …

High risk-human papillomavirus in HNSCC: Present and future challenges for epigenetic therapies

L Ghiani, S Chiocca - International Journal of Molecular Sciences, 2022 - mdpi.com
Head and Neck Squamous Cell Carcinoma (HNSCC) is a highly heterogeneous group of
tumors characterized by an incidence of 650,000 new cases and 350,000 deaths per year …

Gene expression signatures for head and neck cancer patient stratification: are results ready for clinical application?

L Tonella, M Giannoccaro, S Alfieri, S Canevari… - … treatment options in …, 2017 - Springer
Opinion statement Head and neck squamous cell carcinoma (HNSCC) is the sixth leading
cancer by incidence worldwide and considering the recent EUROCARE-5 population-based …

Transcriptomics and Epigenomics in head and neck cancer: available repositories and molecular signatures

MS Serafini, L Lopez-Perez, G Fico, L Licitra… - Cancers of the head & …, 2020 - Springer
For many years, head and neck squamous cell carcinoma (HNSCC) has been considered
as a single entity. However, in the last decades HNSCC complexity and heterogeneity have …

Hypoxia and its influence on radiotherapy response of HPV-positive and HPV-negative head and neck cancer

M Wegge, R Dok, S Nuyts - Cancers, 2021 - mdpi.com
Simple Summary HPV-positive HNSCCs are characterized by a different biology and
demonstrate better therapy response and survival compared to alcohol/tobacco-related …

Genetics and penile cancer: recent developments and implications

J Chahoud, CR Pickering… - Current opinion in …, 2019 - journals.lww.com
Genetics and penile cancer: recent developments and implicat... : Current Opinion in Urology
Genetics and penile cancer: recent developments and implications : Current Opinion in …