Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

A historical review of brain drug delivery

WM Pardridge - Pharmaceutics, 2022 - mdpi.com
The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …

The toxicity of nanoparticles and their interaction with cells: an in vitro metabolomic perspective

M Awashra, P Młynarz - Nanoscale Advances, 2023 - pubs.rsc.org
Nowadays, nanomaterials (NMs) are widely present in daily life due to their significant
benefits, as demonstrated by their application in many fields such as biomedicine …

[HTML][HTML] Photonic and magnetic materials for on-demand local drug delivery

I Armenia, CC Ayllón, BT Herrero, F Bussolari… - Advanced drug delivery …, 2022 - Elsevier
Nanomedicine has been considered a promising tool for biomedical research and clinical
practice in the 21st century because of the great impact nanomaterials could have on human …

Nanoparticles in ocular applications and their potential toxicity

C Yang, J Yang, A Lu, J Gong, Y Yang, X Lin… - Frontiers in molecular …, 2022 - frontiersin.org
Nanotechnology has been developed rapidly in recent decades and widely applied in
ocular disease therapy. Nano-drug delivery systems overcome the bottlenecks of current …

Biomedical Approach of Nanotechnology and Biological Risks: A Mini-Review

DF Silva, ALP Melo, AFC Uchôa, GMA Pereira… - International Journal of …, 2023 - mdpi.com
Nanotechnology has played a prominent role in biomedical engineering, offering innovative
approaches to numerous treatments. Notable advances have been observed in the …

Advantages and potential benefits of using organoids in nanotoxicology

VG Nikonorova, VV Chrishtop, VA Mironov… - Cells, 2023 - mdpi.com
Organoids are microtissues that recapitulate the complex structural organization and
functions of tissues and organs. Nanoparticles have several specific properties that must be …

Nanoparticles-based delivery system and its potentials in treating central nervous system disorders

T Liu, Q Xie, Z Dong, Q Peng - Nanotechnology, 2022 - iopscience.iop.org
Central nervous system (CNS) disorders, such as Alzheimer's disease (AD) and Parkinson's
disease (PD), have become severe health concern worldwide. The treatment of the CNS …

Bioprinting using organ building blocks: spheroids, organoids, and assembloids

LS Baptista, V Mironov, E Koudan… - … Engineering Part A, 2024 - liebertpub.com
Three-dimensional (3D) bioprinting, a promising advancement in tissue engineering
technology, involves the robotic, layer-by-layer additive biofabrication of functional 3D tissue …

Analysis of nanomaterials on biological and environmental systems and new analytical methods for improved detection

S Reagen, JX Zhao - International Journal of Molecular Sciences, 2022 - mdpi.com
The advancing field of nanoscience has produced lower mass, smaller size, and expanded
chemical composition nanoparticles over recent years. These new nanoparticles have …