Myo‐inositol and D‐chiro‐inositol (40: 1) reverse histological and functional features of polycystic ovary syndrome in a mouse model

A Bevilacqua, J Dragotto, A Giuliani… - Journal of cellular …, 2019 - Wiley Online Library
Mice exposed to continuous light undergo functional and histological changes that mimic
those of human Polycystic Ovary Syndrome (PCOS). We herein induced the syndrome by …

High-fat diet exposure from pre-pubertal age induces polycystic ovary syndrome (PCOS) in rats

R Patel, G Shah - Reproduction, 2018 - rep.bioscientifica.com
Polycystic ovary syndrome (PCOS) is associated with hyperandrogenism, oligo-anovulation,
polycystic ovaries and metabolic syndrome. Many researchers reported that PCOS often …

High doses of D-chiro-inositol alone induce a PCO-like syndrome and other alterations in mouse ovaries

A Bevilacqua, J Dragotto, M Lucarelli… - International journal of …, 2021 - mdpi.com
Administration of 1000–1500 mg/day D-Chiro-Inositol (DCIns) or a combination of Myo-
Inositol (MyoIns) and DCIns in their plasma molar ratio (40: 1) for three or more months are …

Genetic rodent models of obesity-associated ovarian dysfunction and subfertility: insights into polycystic ovary syndrome

I Huang-Doran, S Franks - Frontiers in endocrinology, 2016 - frontiersin.org
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women
and a leading cause of female infertility worldwide. Defined clinically by the presence of …

Assessing the effect of MitoQ10 and Vitamin D3 on ovarian oxidative stress, steroidogenesis and histomorphology in DHEA induced PCOS mouse model

G Kyei, A Sobhani, S Nekonam, M Shabani, F Ebrahimi… - Heliyon, 2020 - cell.com
Polycystic ovary syndrome (PCOS) continues to be one of the most complex reproductive
and endocrine disorder among women of reproductive age. Recent reports have identified …

The effects of thylakoid-rich spinach extract and aqueous extract of caraway (Carum carvi L.) in letrozole-induced polycystic ovarian syndrome rats

S Sherafatmanesh, M Ekramzadeh, N Tanideh… - … Medicine and Therapies, 2020 - Springer
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder. The aim
of the present study was to evaluate the effects of the oral administration of thylakoid-rich …

[HTML][HTML] The effect of Melatonin on histological changes of ovary in induced polycystic ovary syndrome model in mice

M Ahmadi, A Rostamzadeh, F Fathi… - Middle East Fertility …, 2017 - Elsevier
Background Antioxidants can be used as adjuvant treatment of polycystic ovary syndrome
(PCOS). Melatonin (MT) is one of the antioxidant that is used nowadays. Objective In this …

[PDF][PDF] The Chances of Infertility in a Patient Presenting with PCOS in Childbearing Age

J Yousaf, S Khadija, N Arshad, MR Amjad, J Gulzar… - Saudi J Med, 2022 - academia.edu
Background: PCOS is a leading cause of infertility globally. Polycystic ovarian syndrome
(PCOS) is a complicated disease pigeon-holed by high testosterone levels, irregular …

Intravaginal administration of metformin hydrochloride loaded cationic niosomes amalgamated with thermosensitive gel for the treatment of polycystic ovary syndrome …

N Saini, RK Sodhi, L Bajaj, RS Pandey, UK Jain… - Colloids and Surfaces B …, 2016 - Elsevier
Background and objective Metformin hydrochloride (MTF-HCl) is extensively recommended
by physicians for the treatment of polycystic ovary syndrome (PCOS). Mechanistically, MTF …

[PDF][PDF] Polycystic ovary morphology (PCOM) in estradiol valerate treated mouse model

L Amini, N Tehranian, M Movahedin… - … Journal of Women's …, 2016 - researchgate.net
Objectives: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in
women of reproductive age. Polycystic ovary (PCO) is a criterion for PCOS. Several animal …