The pharmacology of the cytochrome P450 epoxygenase/soluble epoxide hydrolase axis in the vasculature and cardiovascular disease
I Fleming - Pharmacological reviews, 2014 - ASPET
Over the last 20 years, it has become clear that cytochrome P450 (P450) enzymes generate
a spectrum of bioactive lipid mediators from endogenous substrates. However, studies …
a spectrum of bioactive lipid mediators from endogenous substrates. However, studies …
CYP/PON genetic variations as determinant of organophosphate pesticides toxicity
In the present scenario of increased accumulation of pesticides in the environment, it is
important to understand its impact on human health. The focus is on gene–environment …
important to understand its impact on human health. The focus is on gene–environment …
Personalized antiplatelet therapy according to CYP2C19 genotype after percutaneous coronary intervention: a randomized control trial
X Xie, YT Ma, YN Yang, XM Li, YY Zheng, X Ma… - International journal of …, 2013 - Elsevier
Objective The objective of this study is to compare personalized antiplatelet therapy
according to CYP2C19 phenotype with conventional antiplatelet therapy in patients after …
according to CYP2C19 phenotype with conventional antiplatelet therapy in patients after …
Impact of smoking on the eradication of Helicobacter pylori
J Yu, P Yang, X Qin, C Li, Y Lv, X Wang - Helicobacter, 2022 - Wiley Online Library
Abstract Background and Aim Although the association between the eradication of
Helicobacter pylori (H. pylori) and smoking has been confirmed through a meta‐analysis …
Helicobacter pylori (H. pylori) and smoking has been confirmed through a meta‐analysis …
CYP2C19 loss-of-function is associated with increased risk of hypertension in a Hakka population: a case-control study
N Cai, C Li, X Gu, W Zeng, J Zhong, J Liu… - BMC Cardiovascular …, 2023 - Springer
Background Genetic factors have a certain proportion in the risk factors of hypertension. The
purpose was to investigate the relationship of cytochrome P450 2C19 (CYP2C19) …
purpose was to investigate the relationship of cytochrome P450 2C19 (CYP2C19) …
Smoking increases the likelihood of Helicobacter pylori treatment failure
D Itskoviz, D Boltin, H Leibovitzh, TT Perets… - Digestive and Liver …, 2017 - Elsevier
Background and aims Data regarding the impact of smoking on the success of Helicobacter
pylori (H. pylori) eradication are conflicting, partially due to the fact that sociodemographic …
pylori (H. pylori) eradication are conflicting, partially due to the fact that sociodemographic …
Gene–gene and gene–environment interactions defining lipid-related traits
JM Ordovás, R Robertson… - Current opinion in …, 2011 - journals.lww.com
Epigenetic and epistatic interactions are now becoming more significantly associated with
such disorders, as genomic research digs deeper into the complex nature of genetic …
such disorders, as genomic research digs deeper into the complex nature of genetic …
Genetic variation in NFKB1 and NFKBIA and susceptibility to coronary artery disease in a Chinese Uygur population
HM Lai, XM Li, YN Yang, YT Ma, R Xu, S Pan, H Zhai… - PloS one, 2015 - journals.plos.org
Objectives Coronary artery disease (CAD) is the most common chronic inflammatory
disease worldwide. NF-κ B, a central regulator of inflammation, is involved in various …
disease worldwide. NF-κ B, a central regulator of inflammation, is involved in various …
CYP2C19 phenotype, stent thrombosis, myocardial infarction, and mortality in patients with coronary stent placement in a Chinese population
X Xie, YT Ma, YN Yang, XM Li, X Ma, ZY Fu… - PLoS …, 2013 - journals.plos.org
Background Several studies have indicated that CYP2C19 loss-of-function polymorphisms
have a higher risk of stent thrombosis (ST) after percutaneous coronary interventions (PCIs) …
have a higher risk of stent thrombosis (ST) after percutaneous coronary interventions (PCIs) …
Alcohol consumption and ankle-to-brachial index: results from the cardiovascular risk survey
X Xie, YT Ma, YN Yang, XM Li, F Liu, D Huang, ZY Fu… - PloS one, 2010 - journals.plos.org
Background and Methodology A low ankle-to-brachial index (ABI) is a strong correlate of
cardiovascular disease and subsequent mortality. The relationship between ABI and alcohol …
cardiovascular disease and subsequent mortality. The relationship between ABI and alcohol …