The smallest viable unit of life is the cell. From bacteria to mammals, all cells use the same
nucleic acid-based universal code for the maintenance and inheritance of genetic …

More than 60% of intron-containing genes undergo alternative splicing (AS) in plants. This
number will increase when AS in different tissues, developmental stages, and environmental …

The C-terminal domain (CTD) of the RNA polymerase II largest subunit consists of multiple
heptad repeats (consensus Tyr1–Ser2–Pro3–Thr4–Ser5–Pro6–Ser7), varying in number …

The worldwide decline in amphibians has been attributed to several causes, especially
habitat loss and disease. We identified a further factor, namely “habitat split”—defined as …

Transcription and splicing must proceed over genomic distances of hundreds of kilobases in
many human genes. However, the rates and mechanisms of these processes are poorly …

Appreciable advances into the process of transcript elongation by RNA polymerase II (RNAP
II) have identified this stage as a dynamic and highly regulated step of the transcription …

The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II comprises
multiple tandem conserved heptapeptide repeats, unique to this eukaryotic RNA …

Transcription and pre-mRNA splicing are extremely complex multimolecular processes that
involve protein–DNA, protein–RNA, and protein–protein interactions. Splicing occurs in the …

Mounting evidence suggests that transcription and RNA processing are intimately coupled
in vivo, although each process can occur independently in vitro. It is generally thought that …

The C-terminal domain (CTD) of RNA polymerase II (Pol II) integrates nuclear events by
binding proteins involved in mRNA biogenesis. CTD-binding proteins recognize a specific …