Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …

Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

To support an ever-increasing population, modern agriculture faces numerous challenges
that pose major threats to global food and energy security. Plant-associated microbes, with …

Genetic engineering applications in the field of biofuel are rapidly expanding due to their
potential to boost biomass productivity while lowering its cost and enhancing its quality …

Abstract Development of hyperproducing strains is important for biomanufacturing of
biochemicals and biofuels but requires extensive efforts to engineer cellular metabolism and …

Catharanthine can be coupled with vindoline to synthesize vinblastine and vincristine, which
have been used clinically as potent anticancer drugs. However, the structural complexity …

The use of renewable plant biomass, lignocellulose, to produce biofuels and biochemicals
using microbial cell factories plays a fundamental role in the future bioeconomy. The …

The methylotrophic yeast Pichia pastoris (aka Komagataella phaffii) is one of the most
commonly used hosts for industrial production of recombinant proteins. As a non …

Metabolic engineering holds the promise to transform the chemical industry and to support
the transition into a circular bioeconomy, by engineering cellular biocatalysts that efficiently …

Production of food-related products using microorganisms in an environmentally friendly
manner is a crucial solution to global food safety and environmental pollution issues …