Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown
notable progress. An increasing number of aspects of the immune system are being …

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier
dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus …

Background Patients who completed the originating studies, BREEZE-AD1 (NCT03334396),
BREEZE-AD2 (NCT03334422), and BREEZE-AD7 (NCT03733301), were eligible for …

Tissue fibrosis is characterized by excessive deposition of extracellular matrix (ECM)
molecules. Fibronectin (FN) is a glycoprotein found in the blood and tissues, a key player in …

A subgroup of patients suffering from atopic dermatitis (AD) does not respond to biologics
therapy targeting the key players of type-2 inflammation, and it is an ongoing discussion …

The pathogenic bacterium Staphylococcus aureus is the most common pathogen isolated in
skin-and-soft-tissue infections (SSTIs) in the United States. Most S. aureus SSTIs are caused …

Surface proteins of Gram-positive pathogens are key determinants of virulence that
substantially shape host-microbe interactions. Specifically, these proteins mediate host …

Purpose We aimed to investigate epidermal lipid profiles and their association with skin
microbiome compositions in children with atopic dermatitis (AD). Methods Specimens were …

Background Every day the skin is constantly exposed to several harmful factors that induce
oxidative stress. When the cells are incapable to maintain the balance between antioxidant …

B cells play a key role in our immune system through their ability to produce antibodies,
suppress a pro-inflammatory state, and contribute to central immune tolerance. We aim to …