Leveraging artificial intelligence in the fight against infectious diseases

F Wong, C de la Fuente-Nunez, JJ Collins - Science, 2023 - science.org
Despite advances in molecular biology, genetics, computation, and medicinal chemistry,
infectious disease remains an ominous threat to public health. Addressing the challenges …

Multi-omics data integration considerations and study design for biological systems and disease

S Graw, K Chappell, CL Washam, A Gies, J Bird… - Molecular omics, 2021 - pubs.rsc.org
With the advancement of next-generation sequencing and mass spectrometry, there is a
growing need for the ability to merge biological features in order to study a system as a …

Ensembl 2021

KL Howe, P Achuthan, J Allen, J Allen… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Ensembl project (https://www. ensembl. org) annotates genomes and
disseminates genomic data for vertebrate species. We create detailed and comprehensive …

Rfam 14: expanded coverage of metagenomic, viral and microRNA families

I Kalvari, EP Nawrocki… - Nucleic Acids …, 2021 - academic.oup.com
Rfam is a database of RNA families where each of the 3444 families is represented by a
multiple sequence alignment of known RNA sequences and a covariance model that can be …

ReMap 2022: a database of Human, Mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments

F Hammal, P De Langen, A Bergon… - Nucleic acids …, 2022 - academic.oup.com
Abstract ReMap (https://remap. univ-amu. fr) aims to provide manually curated, high-quality
catalogs of regulatory regions resulting from a large-scale integrative analysis of DNA …

Ensembl Genomes 2022: an expanding genome resource for non-vertebrates

AD Yates, J Allen, RM Amode, AG Azov… - Nucleic acids …, 2022 - academic.oup.com
Abstract Ensembl Genomes (https://www. ensemblgenomes. org) provides access to non-
vertebrate genomes and analysis complementing vertebrate resources developed by the …

[HTML][HTML] Stigma receptors control intraspecies and interspecies barriers in Brassicaceae

J Huang, L Yang, L Yang, X Wu, X Cui, L Zhang, J Hui… - Nature, 2023 - nature.com
Flowering plants have evolved numerous intraspecific and interspecific prezygotic
reproductive barriers to prevent production of unfavourable offspring. Within a species, self …

NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants

L Zhao, J Wang, Y Li, T Song, Y Wu, S Fang… - Nucleic acids …, 2021 - academic.oup.com
Abstract NONCODE (http://www. noncode. org/) is a comprehensive database of collection
and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals …

RNAcentral 2021: secondary structure integration, improved sequence search and new member databases

Nucleic acids research, 2021 - academic.oup.com
RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that
provides a single access point to 44 RNA resources and> 18 million ncRNA sequences from …

Microbial single-cell RNA sequencing by split-pool barcoding

A Kuchina, LM Brettner, L Paleologu, CM Roco… - Science, 2021 - science.org
INTRODUCTION Bacteria heterogeneously activate gene expression programs in response
to environmental changes, stress, and other stimuli. Such behavior may serve as a bet …