Current treatments modalities for major depressive disorder (MDD) mainly target
monoaminergic neurotransmission. However, the therapeutic inadequacy and adverse …

Depression stands as a prominent contributor to global disability, entailing an elevated risk
of suicide. Substantial evidence supports the notion that immune dysregulation may play a …

Objective Patients with hypertension have a risk of depression. Morinda officinalis
oligosaccharides (MOOs) have anti-depressant properties. In this study, we aimed to …

Background Obstructive sleep apnea (OSA) is mainly characterized by sleep fragmentation
and chronic intermittent hypoxia (CIH), the latter one being associated with multiple organ …

Dementia is a syndrome characterized by the deterioration of cognitive function beyond
what is expected. The increased risk of developing this syndrome resulting from established …

INTRODUCTION Depression is considered a prodromal state of Alzheimer's disease (AD),
yet the underlying mechanism (s) by which depression increases the risk of AD are not …

A large body of literature has highlighted the significance of the corticotropin‐releasing
factor (CRF) system in the regulation of neuropsychiatric diseases. Anxiety disorders are …

The most common neurodegenerative diseases (NDDs), such as Alzheimer's disease (AD)
and Parkinson's disease (PD), are the seventh leading cause of mortality and morbidity in …

Cellular senescence is a state of irreversible cellular growth arrest that occurs in response to
various stresses. In addition to exiting the cell cycle, senescent cells undergo many …

Cognitive dysfunction occurs mainly in certain diseases and in the pathological process of
aging. In addition to this, it is also widespread in patients undergoing anesthesia, surgery …