Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells

H Imai, Y Nakagawa - Free Radical Biology and Medicine, 2003 - Elsevier
Reactive oxygen species (ROS) are known mediators of intracellular signal cascades.
Excessive production of ROS may lead to oxidative stress, loss of cell function, and cell …

Osmosensing by bacteria: signals and membrane-based sensors

JM Wood - Microbiology and molecular biology reviews, 1999 - Am Soc Microbiol
Bacteria can survive dramatic osmotic shifts. Osmoregulatory responses mitigate the passive
adjustments in cell structure and the growth inhibition that may ensue. The levels of certain …

Membranes: a meeting point for lipids, proteins and therapies

PV Escribá, JM González‐Ros, FM Goñi… - Journal of cellular …, 2008 - Wiley Online Library
• Introduction• Membrane lipid composition• Membrane lipid structure• Membrane lipid
organization‐Why so many different lipids?‐Lipid mixing and demixing‐Lateral pressure …

Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly

JS Saad, J Miller, J Tai, A Kim… - Proceedings of the …, 2006 - National Acad Sciences
During the late phase of HIV type 1 (HIV-1) replication, newly synthesized retroviral Gag
proteins are targeted to the plasma membrane of most hematopoietic cell types, where they …

[图书][B] The structure of biological membranes

PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

[HTML][HTML] Host lipids in positive-strand RNA virus genome replication

Z Zhang, G He, NA Filipowicz, G Randall… - Frontiers in …, 2019 - frontiersin.org
Membrane association is a hallmark of the genome replication of positive-strand RNA
viruses [(+) RNA viruses]. All well-studied (+) RNA viruses remodel host membranes and …

[HTML][HTML] Phospholipid-cytochrome c interaction: evidence for the extended lipid anchorage

EKJ Tuominen, CJA Wallace, PKJ Kinnunen - Journal of Biological …, 2002 - ASBMB
Binding of cytochrome c (cytc) to fatty acids and acidic phospholipid membranes produces
pronounced and essentially identical changes in the spectral properties of cyt c, revealing …

The functional significance of mitochondrial respiratory chain supercomplexes

A Kohler, A Barrientos, F Fontanesi, M Ott - EMBO reports, 2023 - embopress.org
The mitochondrial respiratory chain (MRC) is a key energy transducer in eukaryotic cells.
Four respiratory chain complexes cooperate in the transfer of electrons derived from various …

The role of lipid–protein interactions in amyloid-type protein fibril formation

GP Gorbenko, PKJ Kinnunen - Chemistry and physics of lipids, 2006 - Elsevier
Structural transition of polypeptide chains into the β-sheet state followed by amyloid fibril
formation is the key characteristic of a number of the so-called conformational diseases. The …

Alternative Conformations of Cytochrome c: Structure, Function, and Detection

L Hannibal, F Tomasina, DA Capdevila… - Biochemistry, 2016 - ACS Publications
Cytochrome c (cyt c) is a cationic hemoprotein of∼ 100 amino acid residues that exhibits
exceptional functional versatility. While its primary function is electron transfer in the …