Update on anti-tumor necrosis factor agents and other new drugs for inflammatory bowel disease
BL Cohen, DB Sachar - Bmj, 2017 - bmj.com
The treatment of inflammatory bowel disease (IBD)—ulcerative colitis (UC) and Crohn's
disease (CD)—has evolved beyond surgery with the introduction of biologic agents …
disease (CD)—has evolved beyond surgery with the introduction of biologic agents …
The future of biosimilars: maximizing benefits across immune-mediated inflammatory diseases
Biologics have transformed the treatment of immune-mediated inflammatory diseases such
as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Biosimilars—biologic …
as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Biosimilars—biologic …
Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised …
Background TNF inhibitors have improved treatment of Crohn's disease, ulcerative colitis,
spondyloarthritis, rheumatoid arthritis, psoriatic arthritis, and chronic plaque psoriasis, but …
spondyloarthritis, rheumatoid arthritis, psoriatic arthritis, and chronic plaque psoriasis, but …
[HTML][HTML] The current state of the art for biological therapies and new small molecules in inflammatory bowel disease
S Paramsothy, AK Rosenstein, S Mehandru… - Mucosal …, 2018 - Elsevier
The emergence of biologic therapies is arguably the greatest therapeutic advance in the
care of inflammatory bowel disease (IBD) to date, allowing directed treatments targeted at …
care of inflammatory bowel disease (IBD) to date, allowing directed treatments targeted at …
Effectiveness and safety of reference infliximab and biosimilar in Crohn disease: a French equivalence study
Background: CT-P13 is a biosimilar of the reference product (RP) infliximab, with
demonstrated efficacy and safety for some inflammatory arthritides. It was approved for the …
demonstrated efficacy and safety for some inflammatory arthritides. It was approved for the …
Systematic review with meta‐analysis: the efficacy and safety of CT‐P13, a biosimilar of anti‐tumour necrosis factor‐α agent (infliximab), in inflammatory bowel …
Y Komaki, A Yamada, F Komaki, D Micic… - Alimentary …, 2017 - Wiley Online Library
Background Biosimilars of anti‐tumour necrosis factor (TNF)‐α agents have now become
clinically available for the treatment of inflammatory bowel diseases (IBD). Aim To perform a …
clinically available for the treatment of inflammatory bowel diseases (IBD). Aim To perform a …
The expanding therapeutic armamentarium for inflammatory bowel disease: how to choose the right drug [s] for our patients?
P Hindryckx, N Vande Casteele, G Novak… - Journal of Crohn's …, 2018 - academic.oup.com
The therapeutic landscape for inflammatory bowel disease [IBD] is rapidly evolving. Two
new biologic drugs, vedolizumab and ustekinumab, have recently entered the marketplace …
new biologic drugs, vedolizumab and ustekinumab, have recently entered the marketplace …
Biosimilars in IBD: from theory to practice
Biologic agents have revolutionized the care management of many life-threatening and
debilitating diseases. As patents for older biologic therapies have begun to expire, the …
debilitating diseases. As patents for older biologic therapies have begun to expire, the …
The rituximab biosimilar CT-P10 in rheumatology and cancer: a budget impact analysis in 28 European countries
Introduction New biosimilars of monoclonal antibodies are anticipated to bring significant
cost savings and increase access to treatment. The rituximab biosimilar CT-P10 has recently …
cost savings and increase access to treatment. The rituximab biosimilar CT-P10 has recently …
Long-Term Clinical Outcomes After Switching from Remicade® to Biosimilar CT-P13 in Inflammatory Bowel Disease
LJT Smits, A Grelack, LAAP Derikx, DJ de Jong… - Digestive diseases and …, 2017 - Springer
Background Limited data are available on long-term clinical outcomes regarding the switch
from Remicade® to the infliximab biosimilar CT-P13 in inflammatory bowel disease (IBD) …
from Remicade® to the infliximab biosimilar CT-P13 in inflammatory bowel disease (IBD) …