Management of human immunodeficiency virus infection in advanced age

M Greene, AC Justice, HW Lampiris, V Valcour - Jama, 2013 - jamanetwork.com
Importance Human immunodeficiency virus (HIV)− positive patients treated with
antiretroviral therapy now have increased life expectancy and develop chronic illnesses that …

Functional impairment, disability, and frailty in adults aging with HIV-infection

KM Erlandson, JA Schrack, CM Jankowski… - Current hiv/aids …, 2014 - Springer
The integration of antiretroviral therapy (ie, ART) into HIV care has dramatically extended the
life expectancy of those living with HIV. However, in comparison to similar HIV-uninfected …

Geriatric syndromes in older HIV-infected adults

M Greene, KE Covinsky, V Valcour… - JAIDS Journal of …, 2015 - journals.lww.com
Background: Geriatric syndromes such as falls, frailty, and functional impairment are
multifactorial conditions used to identify vulnerable older adults. Limited data exist on these …

Co-morbidities in persons infected with HIV: increased burden with older age and negative effects on health-related quality of life

AT Rodriguez-Penney, JE Iudicello… - AIDS patient care and …, 2013 - liebertpub.com
This study sought to determine the synergistic effects of age and HIV infection on medical co-
morbidity burden, along with its clinical correlates and impact on health-related quality of life …

Age, comorbidities, and AIDS predict a frailty phenotype in men who have sex with men

KN Althoff, LP Jacobson, RD Cranston… - … Series A: Biomedical …, 2014 - academic.oup.com
Background. Adults aging with HIV infection are at risk for age-related comorbidities and
syndromes, such as frailty. The objective of this study was to evaluate the expression and …

Polypharmacy, drug–drug interactions, and potentially inappropriate medications in older adults with human immunodeficiency virus infection

M Greene, MA Steinman, IR McNicholl… - Journal of the …, 2014 - Wiley Online Library
Objectives To describe the frequency of medication‐related problems in older adults with
human immunodeficiency virus (HIV) infection. Design Retrospective chart review. Setting …

Antiretroviral therapy intensification for neurocognitive impairment in human immunodeficiency virus

SL Letendre, H Chen, A McKhann, J Roa… - Clinical Infectious …, 2023 - academic.oup.com
Background Neurocognitive impairment (NCI) in people with HIV (PWH) on antiretroviral
therapy (ART) is common and may result from persistent HIV replication in the central …

Quality of life in people living with HIV-associated neurocognitive disorder: a scoping review study

K Alford, S Daley, S Banerjee, JH Vera - PLoS One, 2021 - journals.plos.org
Quality of life (QoL) is recognized as an essential end point in the disease management of
chronic conditions such as HIV with calls to include good QoL as a 'fourth 90'in the 90-90-90 …

Geriatric syndromes: new frontiers in HIV and sarcopenia

KL Hawkins, TT Brown, JB Margolick, KM Erlandson - Aids, 2017 - journals.lww.com
HIV infection, in many circumstances, can now be managed as a chronic disease due to the
marked increase in life expectancy since the introduction of combination antiretroviral …

Physical activity is associated with better neurocognitive and everyday functioning among older adults with HIV disease

PL Fazeli, MJ Marquine, C Dufour, BL Henry… - AIDS and Behavior, 2015 - Springer
We examined the association between physical activity (PA), neurocognitive impairment
(NCI), and instrumental activities of daily living (IADLs) among older HIV+ persons. One …