Complex analysis of retroposed genes' contribution to human genome, proteome and transcriptome

MR Kubiak, MW Szcześniak, I Makałowska - Genes, 2020 - mdpi.com
Gene duplication is a major driver of organismal evolution. One of the main mechanisms of
gene duplications is retroposition, a process in which mRNA is first transcribed into DNA and …

[HTML][HTML] scCensus: Off-target scRNA-seq reads reveal meaningful biology

D He, SM Mount, R Patro - bioRxiv, 2024 - ncbi.nlm.nih.gov
Single-cell RNA-sequencing (scRNA-seq) provides unprecedented insights into cellular
heterogeneity. Although scRNA-seq reads from most prevalent and popular tagged-end …

[HTML][HTML] Circadian oscillation of natural antisense transcripts related to human core clock genes

PN Hanjani, M Golalipour - Reports of Biochemistry & Molecular …, 2021 - ncbi.nlm.nih.gov
Background: Circadian clocks are autonomous intracellular oscillators that synchronize
metabolic and physiological processes with the external signals. So, misalignment of …

[HTML][HTML] Los ARNs no codificantes largos y su vinculación con las patologías testiculares

MF Trovero, A Geisinger - Anales de la Facultad de Medicina, 2019 - scielo.edu.uy
Si bien la porción del genoma destinada a la síntesis de proteínas es muy pequeña,
actualmente se sabe que casi todo el genoma se expresa bajo forma de ARNs no …

Genome-wide ribosome profiling uncovers the role of iron in the control of protein translation

H Barlit, AM Romero, A Gülhan, PK Patnaik… - bioRxiv, 2022 - biorxiv.org
Iron is an essential trace element that serves as a cofactor for enzymes involved in multiple
metabolic pathways, including ribosome biogenesis, protein translation, DNA synthesis and …

Methods for Efficient Processing and Comprehensive Analysis of Single Cell Sequencing Data

D He - 2024 - search.proquest.com
Over the past decade, the rapid development of single-cell RNA-sequencing (scRNAseq)
technology has revolutionized the understanding of cellular differentiation, heterogeneity …

[PDF][PDF] Cytosine Quadruplexes in Duplex DNA may be Non-transient and have Epigenetic Relevance

S Chapman - Toxi App Pharma Insights, 2023 - opastpublishers.com
Guanine quadruplexes folding in single-strand DNA have been extensively studied for some
time. But far less attention has been paid to systems arising in duplex DNA. Furthermore, the …

Molecular modelling and biological implications of non-canonical structures in RNA viruses and long non-coding RNAs

S Chapman - 2023 - oro.open.ac.uk
Guanine quadruplexes folding in single-strand DNA have been extensively studied for some
time. But far less attention has been paid to systems arising in duplex DNA or RNA …

Caracterización del papel de la proteína RBP33 en la regulación de la transcripción no productiva en Trypanosoma brucei

C Gómez Liñan - 2023 - digibug.ugr.es
Durante la última década, gracias a los avances en las tecnologías de secuenciación
masiva que han permitido un análisis más profundo de los transcriptomas de varios …

mRNPs biogenesis perturbation by the bacterial Rho factor: genomic analysis of the recrutment of the THO complex and its subunits

V Beauvais - 2023 - theses.hal.science
The transcription of messenger RNA (mRNA) is a complex process implicating a large
diversity of players at very specific steps. The production of an mRNA also requires its …