New approaches and procedures for cancer treatment: Current perspectives

DT Debela, SGY Muzazu, KD Heraro… - SAGE open …, 2021 - journals.sagepub.com
Cancer is a global health problem responsible for one in six deaths worldwide. Treating
cancer has been a highly complex process. Conventional treatment approaches, such as …

Cancer vaccines: Building a bridge over troubled waters

MLC Sellars, CJ Wu, EF Fritsch - Cell, 2022 - cell.com
Cancer vaccines aim to direct the immune system to eradicate cancer cells. Here we review
the essential immunologic concepts underpinning natural immunity and highlight the …

Recent progress of stem cell therapy in cancer treatment: molecular mechanisms and potential applications

DT Chu, TT Nguyen, NLB Tien, DK Tran, JH Jeong… - Cells, 2020 - mdpi.com
The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …

Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Patient and disease–specific induced pluripotent stem cells for discovery of personalized cardiovascular drugs and therapeutics

DT Paik, M Chandy, JC Wu - Pharmacological reviews, 2020 - ASPET
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for
regenerative therapy, disease modeling, and drug discovery. iPSCs allow for the production …

[HTML][HTML] Antitumor effects of iPSC-based cancer vaccine in pancreatic cancer

X Ouyang, Y Liu, Y Zhou, J Guo, TT Wei, C Liu, B Lee… - Stem cell reports, 2021 - cell.com
Induced pluripotent stem cells (iPSCs) and cancer cells share cellular similarities and
transcriptomic profiles. Here, we show that an iPSC-based cancer vaccine, comprised of …

Pluripotent stem cells: cancer study, therapy, and vaccination

M Barati, M Akhondi, NS Mousavi… - Stem Cell Reviews and …, 2021 - Springer
Abstract Introduction Pluripotent stem cells (PSCs) are promising tools for modern
regenerative medicine applications because of their stemness properties, which include …

Hitchhiking on controlled-release drug delivery systems: opportunities and challenges for cancer vaccines

L Han, K Peng, LY Qiu, M Li, JH Ruan, LL He… - Frontiers in …, 2021 - frontiersin.org
Cancer vaccines represent among the most promising strategies in the battle against
cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the …

Cellular therapeutic potential of genetically engineered stem cells in cancer treatment

EK Sher, A Kalić, A Džidić-Krivić, MB Zećo… - Biotechnology and …, 2023 - Taylor & Francis
Traditional therapeutic approaches in the treatment of cancer have many side effects and
are often ineffective and non-specific, leading to the development of therapy-resistant …

Neoantigen-augmented iPSC cancer vaccine combined with radiotherapy promotes antitumor immunity in poorly immunogenic cancers

KCY Huang, WTL Chen, JY Chen, CY Lee, CH Wu… - npj Vaccines, 2024 - nature.com
Although irradiated induced-pluripotent stem cells (iPSCs) as a prophylactic cancer vaccine
elicit an antitumor immune response, the therapeutic efficacy of iPSC-based cancer …