New approaches and procedures for cancer treatment: Current perspectives
DT Debela, SGY Muzazu, KD Heraro… - SAGE open …, 2021 - journals.sagepub.com
Cancer is a global health problem responsible for one in six deaths worldwide. Treating
cancer has been a highly complex process. Conventional treatment approaches, such as …
cancer has been a highly complex process. Conventional treatment approaches, such as …
Cancer vaccines: Building a bridge over troubled waters
MLC Sellars, CJ Wu, EF Fritsch - Cell, 2022 - cell.com
Cancer vaccines aim to direct the immune system to eradicate cancer cells. Here we review
the essential immunologic concepts underpinning natural immunity and highlight the …
the essential immunologic concepts underpinning natural immunity and highlight the …
Recent progress of stem cell therapy in cancer treatment: molecular mechanisms and potential applications
The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
Patient and disease–specific induced pluripotent stem cells for discovery of personalized cardiovascular drugs and therapeutics
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for
regenerative therapy, disease modeling, and drug discovery. iPSCs allow for the production …
regenerative therapy, disease modeling, and drug discovery. iPSCs allow for the production …
[HTML][HTML] Antitumor effects of iPSC-based cancer vaccine in pancreatic cancer
Induced pluripotent stem cells (iPSCs) and cancer cells share cellular similarities and
transcriptomic profiles. Here, we show that an iPSC-based cancer vaccine, comprised of …
transcriptomic profiles. Here, we show that an iPSC-based cancer vaccine, comprised of …
Pluripotent stem cells: cancer study, therapy, and vaccination
M Barati, M Akhondi, NS Mousavi… - Stem Cell Reviews and …, 2021 - Springer
Abstract Introduction Pluripotent stem cells (PSCs) are promising tools for modern
regenerative medicine applications because of their stemness properties, which include …
regenerative medicine applications because of their stemness properties, which include …
Hitchhiking on controlled-release drug delivery systems: opportunities and challenges for cancer vaccines
Cancer vaccines represent among the most promising strategies in the battle against
cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the …
cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the …
Cellular therapeutic potential of genetically engineered stem cells in cancer treatment
EK Sher, A Kalić, A Džidić-Krivić, MB Zećo… - Biotechnology and …, 2023 - Taylor & Francis
Traditional therapeutic approaches in the treatment of cancer have many side effects and
are often ineffective and non-specific, leading to the development of therapy-resistant …
are often ineffective and non-specific, leading to the development of therapy-resistant …
Neoantigen-augmented iPSC cancer vaccine combined with radiotherapy promotes antitumor immunity in poorly immunogenic cancers
KCY Huang, WTL Chen, JY Chen, CY Lee, CH Wu… - npj Vaccines, 2024 - nature.com
Although irradiated induced-pluripotent stem cells (iPSCs) as a prophylactic cancer vaccine
elicit an antitumor immune response, the therapeutic efficacy of iPSC-based cancer …
elicit an antitumor immune response, the therapeutic efficacy of iPSC-based cancer …