Role of L-arginine in nitric oxide synthesis and health in humans

G Wu, CJ Meininger, CJ McNeal, FW Bazer… - Amino acids in nutrition …, 2021 - Springer
As a functional amino acid (AA), L-arginine (Arg) serves not only as a building block of
protein but also as an essential substrate for the synthesis of nitric oxide (NO), creatine …

Pathophysiology of thrombosis in peripheral artery disease

A Habib, G Petrucci, B Rocca - Current Vascular Pharmacology, 2020 - ingentaconnect.com
Under physiological conditions, peripheral arteries release endogenous vascular-protective
and antithrombotic agents. Endothelial cells actively synthesize vasoactive mediators, which …

Dietary pattern associated with frailty: results from nutrition and health survey in Taiwan

YL Lo, YT Hsieh, LL Hsu, SY Chuang… - Journal of the …, 2017 - Wiley Online Library
Objectives To investigate whether dietary patterns are associated with frailty phenotypes in
an elderly Taiwanese population. Design Cross‐sectional. Setting Nutrition and Health …

Swimming exercise and nano-l-arginine supplementation improve oxidative capacity and some autophagy-related genes in the soleus muscle of aging rats

M Zargani, A Rahimi, ZM Tirani, E Arabzadeh… - Gene, 2023 - Elsevier
The present research aims to evaluate the effect of swimming exercise and chitosan-coated l-
arginine on mitochondrial oxidation, BCL2 Interacting Protein 3 (Bnip3), NIP-like …

Antioxidative defence alterations in skeletal muscle during prolonged acclimation to cold: role of l-arginine/NO-producing pathway

V Petrovic, B Buzadzic, A Korac… - Journal of …, 2008 - journals.biologists.com
SUMMARY Early in cold acclimation (1–7 days), heat is produced by shivering, while late in
cold acclimation (12–45 days), skeletal muscle contributes to thermogenesis by tissue …

The acute effects of L-arginine on hormonal and metabolic responses during submaximal exercise in trained cyclists

SC Forbes, V Harber, GJ Bell - … journal of sport …, 2013 - journals.humankinetics.com
L-arginine may enhance endurance performance mediated by two primary mechanisms
including enhanced secretion of endogenous growth hormone (GH) and as a precursor of …

[HTML][HTML] Kinetics of the utilization of dietary arginine for nitric oxide and urea synthesis: insight into the arginine–nitric oxide metabolic system in humans

F Mariotti, KJ Petzke, D Bonnet, I Szezepanski… - The American journal of …, 2013 - Elsevier
Background: The systemic availability of oral/dietary arginine and its utilization for nitric
oxide (NO) synthesis remains unknown and may be related to a competitive hydrolysis of …

The mechanism of opiorphin-induced experimental priapism in rats involves activation of the polyamine synthetic pathway

ND Kanika, M Tar, Y Tong… - … of Physiology-Cell …, 2009 - journals.physiology.org
Intracorporal injection of plasmids encoding opiorphins into retired breeder rats can result in
animals developing a priapic-like condition. Microarray analysis demonstrated that following …

The vascular endothelial growth factor trap aflibercept induces vascular dysfunction and hypertension via attenuation of eNOS/NO signaling in mice

Z Dong, M Wu, Y Zhang, Q Wang, C Liang… - Acta Pharmacologica …, 2021 - nature.com
Aflibercept, as a soluble decoy vascular endothelial growth factor receptor, Which has been
used as a first-line monotherapy for cancers. Aflibercept often causes cardiovascular …

The acute effects of a low and high dose of oral l-arginine supplementation in young active males at rest

SC Forbes, GJ Bell - Applied Physiology, Nutrition, and …, 2011 - cdnsciencepub.com
l-arginine (2-amino-5-guanidinovaleric acid) is a conditionally essential amino acid.
Intravenous (IV) administration of l-arginine invokes a large metabolic (nitrate/nitrite (NOx)) …