Gut–brain axis as a pathological and therapeutic target for neurodegenerative disorders

ARL Toledo, GR Monroy, FE Salazar, JY Lee… - International Journal of …, 2022 - mdpi.com
Human lifestyle and dietary behaviors contribute to disease onset and progression.
Neurodegenerative diseases (NDDs), considered multifactorial disorders, have been …

Enabling multiplexed electrochemical detection of biomarkers with high sensitivity in complex biological samples

SS Timilsina, P Jolly, N Durr, M Yafia… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus The ability to perform multiplexed detection of various biomarkers within
complex biological fluids in a robust, rapid, sensitive, and cost-effective manner could …

Blood biomarkers for stroke diagnosis and management

J Kamtchum-Tatuene, GC Jickling - Neuromolecular medicine, 2019 - Springer
Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …

Rapid computer‐aided diagnosis of stroke by serum metabolic fingerprint based multi‐modal recognition

W Xu, J Lin, M Gao, Y Chen, J Cao, J Pu… - Advanced …, 2020 - Wiley Online Library
Stroke is a leading cause of mortality and disability worldwide, expected to result in 61
million disability‐adjusted life‐years in 2020. Rapid diagnostics is the core of stroke …

[HTML][HTML] Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives

S Patil, R Rossi, D Jabrah, K Doyle - Frontiers in medical technology, 2022 - frontiersin.org
Stroke is one of the leading causes of disability worldwide. Early diagnosis and treatment of
stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke …

Rapid triage for ischemic stroke: a machine learning-driven approach in the context of predictive, preventive and personalised medicine

Y Zheng, Z Guo, Y Zhang, J Shang, L Yu, P Fu, Y Liu… - EPMA Journal, 2022 - Springer
Background Recognising the early signs of ischemic stroke (IS) in emergency settings has
been challenging. Machine learning (ML), a robust tool for predictive, preventive and …

Stroke and emerging blood biomarkers: a clinical prospective

A Gkantzios, D Tsiptsios, S Karatzetzou… - Neurology …, 2022 - mdpi.com
Stroke constitutes the primary source of adult functional disability, exhibiting a paramount
socioeconomic burden. Thus, it is of great importance that the prediction of stroke outcome …

Neurovascular unit as a source of ischemic stroke biomarkers—limitations of experimental studies and perspectives for clinical application

A Steliga, P Kowiański, E Czuba, M Waśkow… - Translational stroke …, 2020 - Springer
Cerebral stroke, which is one of the most frequent causes of mortality and leading cause of
disability in developed countries, often leads to devastating and irreversible brain damage …

The clinical and mechanistic roles of bile acids in depression, Alzheimer's disease, and stroke

W Lirong, Z Mingliang, L Mengci, G Qihao… - …, 2022 - Wiley Online Library
The burden of neurological and neuropsychiatric disorders continues to grow with significant
impacts on human health and social economy worldwide. Increasing clinical and preclinical …

Applications of laboratory findings in the prevention, diagnosis, treatment, and monitoring of COVID-19

Z Meng, S Guo, Y Zhou, M Li, M Wang… - Signal transduction and …, 2021 - nature.com
The worldwide pandemic of coronavirus disease 2019 (COVID-19) presents us with a
serious public health crisis. To combat the virus and slow its spread, wider testing is …