Latest developments in metal complexes as anticancer agents

R Paprocka, M Wiese-Szadkowska… - Coordination Chemistry …, 2022 - Elsevier
Every year novel biologically active compounds are designed as antitumor agents. This
review covers and highlights some of the most important findings described during 2018 …

Recent developments on other platinum metal complexes as target-specific anticancer therapeutics

TS Prathima, B Choudhury, MG Ahmad… - Coordination Chemistry …, 2023 - Elsevier
Numerous biologically active metal complexes are reported for their unique features and
enhanced functions, particularly towards the inhibition of cancer progression. With the …

[HTML][HTML] Recent advances in nanocarrier-assisted therapeutics delivery systems

S Su, PM Kang - Pharmaceutics, 2020 - mdpi.com
Nanotechnologies have attracted increasing attention in their application in medicine,
especially in the development of new drug delivery systems. With the help of nano-sized …

Niosomes: a novel targeted drug delivery system for cancer

M Moghtaderi, K Sedaghatnia, M Bourbour… - Medical Oncology, 2022 - Springer
Recently, nanotechnology is involved in various fields of science, of which medicine is one
of the most obvious. The use of nanoparticles in the process of treating and diagnosing …

Target based chemotherapeutic advancement of ruthenium complexes

BK Kundu, S Mukhopadhyay - Coordination Chemistry Reviews, 2021 - Elsevier
Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …

Bioactivity and development of small non-platinum metal-based chemotherapeutics

MG Ferraro, M Piccolo, G Misso, R Santamaria, C Irace - Pharmaceutics, 2022 - mdpi.com
Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Ruthenium complexes as promising candidates against lung cancer

Q Sun, Y Li, H Shi, Y Wang, J Zhang, Q Zhang - Molecules, 2021 - mdpi.com
Lung cancer is one of the most common malignancies with the highest mortality rate and the
second-highest incidence rate after breast cancer, posing a serious threat to human health …

Ruthenium complexes: An alternative to platinum drugs in colorectal cancer treatment

KM Mahmud, MS Niloy, MS Shakil, MA Islam - Pharmaceutics, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the intimidating causes of death around the world. CRC
originated from mutations of tumor suppressor genes, proto-oncogenes and DNA repair …

Review of comparative studies of cytotoxic activities of Pt (II), Pd (II), Ru (II)/(III) and Au (III) complexes, their kinetics of ligand substitution reactions and DNA/BSA …

RO Omondi, SO Ojwach, D Jaganyi - Inorganica Chimica Acta, 2020 - Elsevier
New concepts and various strategies are being explored to improve the cytotoxicity of metal-
based complexes. One of those strategies is to fine-tune the substitution kinetics of metallo …

Nanoparticle-guided brain drug delivery: Expanding the therapeutic approach to neurodegenerative diseases

C Riccardi, F Napolitano, D Montesarchio, S Sampaolo… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …