Cytotoxicity and mechanism of action of metal complexes: An overview
After the discovery of cisplatin, many metal compounds were investigated for the therapy of
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …
Platinum (II) and Ruthenium (II) complexes in medicine: Antimycobacterial and Anti-HIV activities
Approximately 100 million people worldwide are affected by M. Tuberculosis (Mtb), a
contagious disease which causes death in humans and is considered to be quite deadly …
contagious disease which causes death in humans and is considered to be quite deadly …
Advantageous reactivity of unstable metal complexes: Potential applications of metal-based anticancer drugs for intratumoral injections
Injections of highly cytotoxic or immunomodulating drugs directly into the inoperable tumor is
a procedure that is increasingly applied in the clinic and uses established Pt-based drugs. It …
a procedure that is increasingly applied in the clinic and uses established Pt-based drugs. It …
Plecstatin-1 induces an immunogenic cell death signature in colorectal tumour spheroids
D Wernitznig, SM Meier-Menches, K Cseh… - Metallomics, 2020 - academic.oup.com
Organometallic metal (arene) anticancer agents were believed to confer low selectivity for
potential cellular targets. However, the ruthenium (arene) pyridinecarbothioamide (plecstatin …
potential cellular targets. However, the ruthenium (arene) pyridinecarbothioamide (plecstatin …
Hybrid nano-architectures loaded with metal complexes for the co-chemotherapy of head and neck carcinomas
Head and neck squamous cell carcinomas (HNSCCs) are a complex group of malignancies
that affect different body sites pertaining to the oral cavity, pharynx and larynx. Current …
that affect different body sites pertaining to the oral cavity, pharynx and larynx. Current …
Synthesis, Characterization, PXRD Studies, Theoretical Calculation, and Antitumor Potency Studies of a Novel N, O‐Multidentate Chelating Ligand and Its Zr (IV), V (IV …
A new series of Zr (IV), V (IV), Ru (III), and Cd (II) complexes with the ligand N‐((5‐hydroxy‐4‐
oxo‐4H‐pyran‐3‐yl) methylene)‐2‐(p‐tolylamino) acetohydrazide (H2L) have been …
oxo‐4H‐pyran‐3‐yl) methylene)‐2‐(p‐tolylamino) acetohydrazide (H2L) have been …
Cu (II), Co (II), Mn (II) complexes with 5-phenyltetrazole and polypyridyl ligands: Synthesis, characterization and evaluation of the cytotoxicity and antimicrobial activity
JA Eremina, EA Ermakova, KS Smirnova… - Polyhedron, 2021 - Elsevier
In this work, six new mixed-ligand Cu (II), Co (II), Mn (II) complexes with 5-phenyltetrazole
(HL) and polypyridine ligands (phen–1, 10-phenanthroline, dmbipy–2, 2′-bi-4-picoline …
(HL) and polypyridine ligands (phen–1, 10-phenanthroline, dmbipy–2, 2′-bi-4-picoline …
Mechanistic studies of arene–ruthenium (II) complexes with carbothioamidopyrazoles as alternative cancer drugs
P Hikisz, E Namiecińska, P Paneth, E Budzisz - Molecules, 2023 - mdpi.com
Arene–ruthenium (II) complexes with carbothioamidopyrazoles at the C-2 and C-5 positions
have been recognized as chemotherapeutic agent alternatives to cisplatin and its oxaliplatin …
have been recognized as chemotherapeutic agent alternatives to cisplatin and its oxaliplatin …
Breast cancer chemotherapeutic options: A general overview on the preclinical validation of a multi-target Ruthenium (III) complex lodged in nucleolipid nanosystems
In this review we have showcased the preclinical development of original amphiphilic
nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the …
nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the …
Macromolecules incorporating transition metals in the treatment and detection of cancer and infectious diseases: Progress over the last decade
A Abd-El-Aziz, SA Ahmed, X Zhang, N Ma… - Coordination Chemistry …, 2024 - Elsevier
The past decade has seen tremendous demand for the production of new materials based
on metal-containing macromolecules. Many research groups have dedicated their time and …
on metal-containing macromolecules. Many research groups have dedicated their time and …