Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Multiple sclerosis–a review

R Dobson, G Giovannoni - European journal of neurology, 2019 - Wiley Online Library
Multiple sclerosis (MS) is the commonest non‐traumatic disabling disease to affect young
adults. The incidence of MS is increasing worldwide, together with the socioeconomic …

Central nervous system macrophages in progressive multiple sclerosis: relationship to neurodegeneration and therapeutics

E Kamma, W Lasisi, C Libner, HS Ng… - Journal of …, 2022 - Springer
There are over 15 disease-modifying drugs that have been approved over the last 20 years
for the treatment of relapsing–remitting multiple sclerosis (MS), but there are limited …

Human autoimmune diseases: a comprehensive update

L Wang, FS Wang, ME Gershwin - Journal of internal medicine, 2015 - Wiley Online Library
There have been significant advances in our understanding of human autoimmunity that
have led to improvements in classification and diagnosis and, most importantly, research …

An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis

N Garg, TW Smith - Brain and behavior, 2015 - Wiley Online Library
Background Multiple sclerosis is an acquired demyelinating disease of the central nervous
system. It is the second most common cause of disability in adults in United States after head …

Effect of nutrition on neurodegenerative diseases. A systematic review

VE Bianchi, PF Herrera, R Laura - Nutritional neuroscience, 2021 - Taylor & Francis
Neurodegenerative diseases are characterized by the progressive functional loss of
neurons in the brain, causing cognitive impairment and motoneuron disability. Although …

Podoplanin in inflammation and cancer

M Quintanilla, L Montero-Montero, J Renart… - International journal of …, 2019 - mdpi.com
Podoplanin is a small cell-surface mucin-like glycoprotein that plays a crucial role in the
development of the alveoli, heart, and lymphatic vascular system. Emerging evidence …

Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

NK cells in autoimmune diseases: protective or pathogenic?

M Liu, S Liang, C Zhang - Frontiers in Immunology, 2021 - frontiersin.org
Autoimmune diseases generally result from the loss of self-tolerance (ie, failure of the
immune system to distinguish self from non-self), and are characterized by autoantibody …

White matter diseases with radiologic-pathologic correlation

N Sarbu, RY Shih, RV Jones, I Horkayne-Szakaly… - Radiographics, 2016 - pubs.rsna.org
White matter diseases include a wide spectrum of disorders that have in common
impairment of normal myelination, either by secondary destruction of previously myelinated …